ASSOCIATION OF EDA GENE POLYMORPHISMS rs 372024, rs 3764746, rs 3795170 IN SKELETAL CLASS I CASES WITH DENTAL CROWDING
Journal Title: GJRA-Global Journal For Research Analysis - Year 2019, Vol 8, Issue 8
Abstract
The EDA gene, associated with X linked hydrotic form of Ectodermal Dysplasia, its mutations could potentially lead to differential gene expression that causes large tooth phenotype, which has been suggested to cause dental crowding. We analyzed the association of genetic polymorphisms in EDA gene variants rs 372024, rs 3764746, and rs 3795170 among Skeletal Class I crowding cases using blood samples of 30 cases and 30 controls, which were subjected to PCR amplication and DNA sequencing. Based on the statistical analysis using the Z test we found CG and GG genotype for rs3764746 and GT and TT genotype for rs3795170 showed a statistically signicant result. These results suggest that EDA gene variants rs3764746 and rs3795170 could be genetic markers for dental crowding in our population while EDA gene variant rs372024 did not show any signicant association in our population. These ndings can provide in-depth knowledge, regarding the genetic inuences on the incidence of crowding of teeth.
Authors and Affiliations
Dr. Aarushi Agarwal
Keywords
Related Articles
- EP ID EP636262
- DOI -
- Views 80
- Downloads 0
Harmful Effect of Chemicals Present in Junk Food
Junk food is unhealthy, low in fibre, high in fat and salt, high in sugar in liquid form, it induces obesity Studies have shown that despite being unhealthy, due to better taste such foods are gaining popularity The term...
NESTING BEHAVIOR OF PAINTED STORK (MYCTERIA LEUCOCEPHALA) AT NAVSARI RAILWAY STATION, NAVSARI DISTRICT, GUJARAT
The Painted stork is long legged wader bird belonging to Ciconiidae family. Study was carried out on nesting behavior of painted stork (Mycteria Leucocephala) at Navsari Railway Station, Navsari district, Gujarat, India...
Technical Analysis and Stock Market Return
Moving averages and moving averages crossover is a significant technical analysis tool on any index or stock which helps to understand the price behavior of the shares, the signals given by them and the major turning poi...
ASSESSMENT OF THERAPEUTIC EFFICACY AND SAFETY OF DELPHINIUM DENUDATUM WALL (JADWAR) AND LOCAL APPLICATION OF IRIS FLORENTINA (ROGHAN SOSAN) IN PAINFUL DIABETIC NEUROPATHY: A RANDOMISED SINGLE BLIND STANDARD CONTROLLED STUDY
The current study was conducted to assess the efficacy and safety of Delphinium denudatum (Jadwar)and roghan sosan in patients with painful diabetic neuropathy. A randomised single-blind standard controlled trial was car...
Performance Evaluation of Banks- A Case Study of BDCCB of Belgaum District
The banking sector has been playing key role in the development of Indian economy. The co-operative banks in India have been financing rural and urban borrowers to invest in production activities from the day of their in...