Association of quality of life with disease severity in psoriasis
Journal Title: International Journal of Medical and Health Research - Year 2018, Vol 4, Issue 9
Abstract
Background: Psoriasis has been shown to affect physically, socially as well as psychologically, thus affecting the day to day life of patients. Aims and Objective: To measure quality of life and its relationship with severity of disease in psoriasis patients. Materials and Method: Hundred and ten patients with psoriasis were studied at the Department of Dermatology, Era's Lucknow Medical College and Hospital, Lucknow for one year. Disease severity using Psoriasis Area and Severity Index (PASI) was compared with quality of life of patients which was measured using WHO-BREF Quality of life scale standardized to 100-point with lower scores indicating poor quality and higher scores indicating good quality of life. Detailed demographic and clinical profile of each patient was also recorded. Results: Mean age of patients was 33.64+8.55 years, majority were males (62%) and urban residents (73%). Housewives (42%) were the most common occupational groups. Majority had gradual onset (59%), maximum (47%) had onset of symptoms for <1 year, 11% had pruritus, >3 sites were involved in 52% and koebernisation in 45%. A total of 46% reported of seasonal variability. Severity of disease (PASI) scores were 0-24, 25-48 and >48 in 61%, 28% and 11% cases respectively. Mean overall QOL score of study population was 59.23+ 7.28. Mean scores for physical, psychological, social and environmental domains were 16.12+1.62, 13.19+ 4.24, 7.11+1.42 and 22.61+ 6.11 respectively. Mean quality of life scores of patients with higher PASI scores (25-48 and >48) were significantly lower as compared to those for lower PASI scores (0-24) (p<0.001). Conclusion: The findings of study showed that quality of life of patients with psoriasis was highly impaired and it was related with the severity of disease too.
Authors and Affiliations
Dr. Deepak Sharma, Dr. Priyanka Sharma
Keywords
Related Articles
- EP ID EP587642
- DOI -
- Views 145
- Downloads 0
Histopathological spectrum of polypoid lesions of nasal cavity in a tertiary care center in Pondicherry
Lesions occurring in the nasal cavity usually present as polypoid masses. Majority of these lesions are non-neoplastic and tumors occurring in the nasal cavity often masquerade as a chronic inflammatory condition. Even t...
Study of troponin-T, troponin-I and CK-MB in acute myocardial infarction
Measuring cardiac biomarkers can be a step toward making a diagnosis for a condition. Whereas cardiac imaging often confirms a diagnosis, simpler and less expensive cardiac biomarker measurements can advise a physician w...
Neurofibroma of the scrotum: A rare identity in surgical practice
A 42-year-old male patient reported twith a swelling in the scrotum, Extratesticular localization of neurofibroma have been reported extremely rarely in the literature. We are reporting such rare case with a different pr...
Assessment of effectiveness of Tenofovir and entecavir for the treatment of nucleos (t) ide-naïve patients with chronic Hepatitis B
Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus (HBV). It is a major global health problem. It can cause chronic infection and puts people at high risk of death from cirrhosi...
Clinical, urodynamic and ultrasound study for the evaluation of urinary incontinence associated with genital prolapse
Objectives: Urodynamic and ultrasound study for the evaluation of urinary incontinence associated with genital prolapse. Comparing the accuracy of clinical assessment versus ultrasound study in detecting stress urinary i...