Association of Serum Vitamin D Levels and Recurrent Wheezing in Children
Journal Title: Journal of Clinical and Diagnostic Research - Year 2018, Vol 12, Issue 10
Abstract
ABSTRACT Introduction: Wheezing is quite frequently observed in preschool children. There are many risk factors responsible for the development of recurrent wheezing; recently, vitamin D has gained significant interest. Aim: To study the association of serum vitamin D (25(OH) D) level and recurrent wheeze in children less than three years of age. Materials and Methods: This was a Case-control study conducted at a tertiary care hospital in New Delhi. Children less than three years with recurrent wheeze along with age matched controls were subjected to analysis of serum vitamin D, calcium, phosphate and alkaline phosphatase levels. The data was analysed to find out an association between the serum levels of vitamin D and recurrent wheezing. Results: A strong association between the low serum Vitamin D levels and the recurrent wheeze (p=0.001) was found. Also, high levels of serum alkaline phosphatase were seen among the children with recurrent wheezes (677 vs 317 IU/L, p<0.001) and it had an inverse relation with serum vitamin D levels (k-0.688). Conclusion: Low serum vitamin D level is strongly associated with recurrent wheezing in preschool children.
Authors and Affiliations
Afreen Khan, Jogender Yadav, Pradeep Debata, Jagannath Mohapatra, Bhaskar Kabi
Keywords
Related Articles
- EP ID EP529359
- DOI 10.7860/JCDR/2018/36994.12110
- Views 106
- Downloads 0
Comparative Evaluation of Serum Malondialdehyde (MDA) Level in Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma
ABSTRACT Introduction: Lipid peroxidation, which is induced by reactive oxygen species, is involved in the pathogenesis of malignancy. This lipid peroxidation levels are indicated by Malondialdehyde (MDA), which is the m...
Second Degree Mobitz Type 1 Block in Dengue Haemorrhagic Fever: A Rare Manifestation
ABSTRACT Dengue is an arboviral disease caused by a Flavivirus. It is spread by the bite of Aedes aegypti mosquito. Spectrum of this disease ranges from mild self-limiting fever to potentially fatal severe multiorgan dys...
Gitelman Syndrome in a Case of Diabetic Kidney Disease: A Diagnostic and Therapeutic Dilemma
ABSTRACT Gitelman syndrome is an autosomal recessive disorder that usually presents with hypokalemia, hypomagnesemia, hypocalciuria and normal blood pressure. In contrast to Bartter syndrome it presents in late adulthood...
Evaluation of the Vertical Bone Height of the Palate using CBCT for Placing Micro Implants- A Pilot Study
ABSTRACT Introduction: Determining an ideal anatomical location for mini-implant placement is very crucial for successful use of mini-implants in an orthodontic setup. Some of the factors that should be considered while...
Morphometric Study of Foramina Transversaria and the Incidence of Accessory Foramina in Cervical Spine of Indian Population
ABSTRACT Introduction: The Foramina Transversaria (FT) are known to exhibit variations in their size, shape and they may be absent or duplicated/triplicated. The deformation of foramina may result in derangement of neuro...