Association of Subclinical Hypothyroidism with Metaboic Syndrome and its Parameters
Journal Title: International Journal of Interdisciplinary and Multidisciplinary Studies (IJIMS) - Year 2015, Vol 2, Issue 3
Abstract
Metabolic Syndrome (MetS) (also known as syndrome X ) is a cluster of cardiovascular risk factors, where the primary etiology is suggested to be related to Insulin Resistance (IR). The components of MetS include dyslipidemia, hypertension, abdominal obesity & hyperglycemia. Thyroid hormones also influence the parameters of MetS such as high density lipoprotein (HDL), Triglycerides (TGL) & Blood pressure (BP). Subclinical Hypothyroidism (SCH) defined as an asymptomatic condition with high thyroid stimulating hormone (TSH) has been suggested as a risk factor for cardiovascular disorders. The aim of the present study was to determine the association of SCH with metabolic syndrome . For the study 30 patients fulfilling 3 or more American National Cholesterol Education Program Adult III Treatment Panel (NCEP ATP III) criteria were diagnosed with MetS and considered as case group and 30 controls were included in the study, each group consisted of both sexes and the participants were between age of 27-73 years. Various parameters such as waist circumference, TGL, HDL, blood pressure and fasting glucose along with TSH was measured. A significant increase was seen in the mean TSH of patients with MetS when compared to control group (p=0.000) was found. 96.66% of the case group had SCH when compared with 60% of individuals from the control group. It may be concluded that SCH is significantly associated with metabolic syndrome.
Authors and Affiliations
Krithika B, Santhi Slambanan
Keywords
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