ATROPINE INDUCED PSYCHOSIS: A CONSEQUENCE DURING THE ORGANOPHOSPHATE POISONING TREATMENT
Journal Title: INTERNATIONAL JOURNAL OF PURE MEDICAL RESEARCH - Year 2018, Vol 3, Issue 7
Abstract
A t r o p i n e i s a k n o w n a n d a n e s t a b l i s h e d a n t i d o t e i n organophosphorus poisonings and it also helps to improve the extrapyramidal symptoms as it can cross the blood brain barrier. In the literature, the reports of atropine intoxication is not rare. Nevertheless, the reports of atropine abuse leading to psychosis are infrequent. Here, we present the case of 39 year old male patient who received atropine as part of antidote therapy for Organophosphorus poisoning and the drug was within the recommended dose. After the drug was administered, the patient developed restlessness, delirium, hallucinations, irrelevant talk along with tachycardia and dilated pupils not reacting to light suggesting possible 'anti-cholinergic abuse'. The patient was managed by titrating down the atropine's dose and administration of haloperidol and promethazine.
Authors and Affiliations
Madiha Nooreen, Saima Aziz, Ayesha Habeeb, Shafia Fatima, Zeba Fatima
POSTOBSTRUCTIVE NEGATIVE PRESSURE PULMONARY EDEMA
Acute pulmonary negative pressure edema (NPPE) also known as post-obstructive pulmonary edema is a life-threatening clinical scenario in which pulmonary edema develops immediately after upper airway obstruction. A review...
ANTI-MUTAGENICEFFECT OF DALBERGIA LATIFOLIA ON SWISS ALBINO MICE
Aim of The Study: The present study was designed to evaluate the anti-mutagenic potential of Methanolic extract of Dalbergia latifolia, using micronucleus (MN) assay in mice bone marrow. Materials and methods: The anti-m...
HYPERLIPIDEMIA IN DIABETIC AND HYPOTHYROID PATIENTS: CASE CONTROL STUDY
BACKGROUND: Hyperlipidemia is the leading cause of death in the CVD patients. Diabetes and hypothyroidism are the two main endocrine risk factors for hyperlipidemia. Diabetes is associated with altered metabolism of trig...
COMPARATIVE CLINCIAL – HISTOLOGICAL STUDY OF SEMINOGRAMS AND TESTICLE BIOPSIES IN MALE INFERTILITY
Male infertility represents a problem studied by urologists, pathologists, geneticists, immunologists and researchers from many different disciplines, considering its worldwide growth and the complexity of diagnostics. T...
CONGENITAL ADRENAL HYPERPLASIA DIAGNOSIS STILL A CHALLENGE
Background: Congenital adrenal hyperplasia is one of the main pediatric referent, due to genital ambiguity and mortality of neonates as a result of dehydration and shock. The matter is exacerbated by high degree of consa...