B-Cell Targets to Treat Antibody-Mediated Rejection in Transplantation
Journal Title: International Journal of Transplantation Research and Medicine - Year 2016, Vol 2, Issue 2
Abstract
Abstract: Antibody-mediated rejection (AMR) in allograft transplantation can be defined with a rapid increase in the levels of specific serological parameters after organ transplantation, presence of donor specific antibodies (DSAs) against human leukocyte antigen (HLA) molecules, blood group (ABO) antigens and/or endothelial cell antigens (e.g. MICA, ECA, Vimentin, or ETAR) and also particular histological parameters.
Treatment of Coronary Artery Fistula Post-Cardiac Transplantation with Covered Stent: A Case Study and Review of Literature
The majority of coronary artery fistulas are congenital and discovered incidentally on coronary angiography. Coronary artery fistulas may also develop after cardiac transplantation as a complication of endomyocardial bio...
Skin Lesions after Kidney Transplantation: An updated Review Including Recent Rare Cases
Skin disease is a significant cause of morbidity in chronically immunosuppressed patients, including organ transplant recipients. Cutaneous neoplasms are much more common in renal transplant recipients than in the genera...
Case Report and Review of the Literature: Resolution of Lithium-Induced Nephrogenic Diabetes Insipidus with Pre-Emptive Living Related Kidney Transplantation for End-Stage Renal Disease
Long-term lithium therapy is known to cause renal dysfunction, including nephrogenic diabetes insipidus (nDI) and chronic tubulointerstitial nephropathy, which may progress to end-stage renal disease (ESRD) in approximat...
Complications after Heart Transplantation: Hope for the Best, but Prepare for the Worst
For selected patients living with the most advanced stages of heart failure, cardiac transplantation is considered the gold-standard treatment, providing substantial improvements in survival and quality of life. However,...
Transplantation of Decellularized Venous Valvular Grafts in an Ovine Model
The surgical treatment of end-stage chronic venous insufficiency involves valvular repair or transplantation to restore venous valve function and structure. Current valve substitutes can have issues with durability, thro...