Bacteriological profile and antimicrobial resistance patterns of bloodstream infections in a tertiary care hospital Bikaner, Northern western Rajasthan
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 7
Abstract
BSIs infection is most serious complication and significant cause of morbidity and mortality at worldwide. Different etiological agents like Staphylococcus aureus, , Escherichia coli, and Klebsiella pneumonia are major cause of BSIs. Due to geographical variation and different antimicrobial agent may change prevalence and antimicrobial susceptibility of microorganisms. The present study was aimed to analyze the various microorganisms causing BSIs and their antimicrobial resistance profile in a major tertiary care hospital, Bikaner, Northern Western Rajasthan to to guide the clinicians to choose an appropriate antimicrobial therapy for treatment of BSIs. Blood samples in brain heart infusion (BHI) broth submitted to the microbiology laboratory for culture and sensitivity during a period of 1 year were included in the study. Samples were processed as per standard protocol of laboratory for isolation and identification. The antimicrobial susceptibility profile of bacterial isolates was determined by the disc diffusion method as per Clinical and Laboratory Standards Institute (CLSI) guidelines. Out of 200 samples 48 samples are culture positive in which Gram positive cocci are most significant microorganism isolated. Most of the Gram-positive cocci (GPC) were susceptible to vancomycin and linezolid. Most of the Gram-negative bacilli (GNB) showed sensitivity to imipenem.
Authors and Affiliations
Dr. Rahul Acharya
Keywords
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