Bacteriological Profile and Antimicrobial Susceptibility Pattern of Isolates from Patients with Septicaemia in Butembo, Democratic Republic of the Congo
Journal Title: Journal of Advances in Microbiology - Year 2017, Vol 6, Issue 4
Abstract
Background: Emergence of antimicrobial resistance has limited treatment options against bloodstream infections. This study aimed to determine bacterial isolates from blood culture of patients with bloodstream infection and their sensitivity to antimicrobials at patients attending the Central Laboratory of Research of the “Université Catholique du Graben” (UCG) in Butembo. Methodology: This was a cross-sectional study adopting a descriptive approach, conducted from January, 2015 to December, 2016. Blood was collected from a peripheral vein using an aseptic technique. The culture and the antimicrobial susceptibility testing were done by using standard methods according to the Clinical Laboratory Standard Institute guidelines. Results: The most isolated bacteria from blood culture of patient with bloodstream infections were Staphylococcus aureus (39.8%), Listeria spp. (17.4%), Moraxella spp. (14.3%), Bacillus spp. (13.4%) and Klebsiella rhinoscleromatis (4.1%). All bacterial isolates tested for sensitivity were resistant to the group of β-lactamine antibiotics except S. aureus which was sensitive only to vancomycin. It was also observed that all the bacterial species have a Multiple Antibiotic Resistance Index greater than 0.2. Conclusion: Bloodstream infections are life-threatening conditions, continuous and regular monitoring of antimicrobial susceptibility pattern of responsible bacteria is needed. From this study, we suggested gentamicin, doxycycline, ciprofloxacin, and levofloxacin as the first line antibiotics of choice for empiric treatment of bloodstream infections in Butembo.
Authors and Affiliations
Gabriel Kambale Bunduki, Zacharie Tsongo Kibendelwa, Adélard Kalima Nzanzu
Keywords
Related Articles
- EP ID EP338304
- DOI 10.9734/JAMB/2017/38055
- Views 85
- Downloads 0
Induction and Expression of Chitinases from Four Sub Species of Bacillus thuringiensis
Chitin is a naturally occurring linear polymer of N-acetylglucosamine and the major structural component of fungal cell walls and exoskeletons of insects and arthropods. Chitinases are the enzymes that breakdown chitin t...
Antibiotic Susceptibility Profile of Bacterial Pathogens Isolated from Malabor Hostel Tap Water, Calabar- Nigeria
The antibiotic resistance and susceptibility profiles of some bacterial isolates including Listeria monocytogenes, Erwinia stewartii, Legionella pneumophilia, Carnobacterium gallinarum, Staphylococcus caseolyticus, Enter...
Prevalence of Listeria monocytogenes in Fresh and Raw Fish, Chicken and Beef
There has been recent outbreaks of food poisoning associated with Listeria monocytogenes. Most of the outbreaks were attributed to fresh meat and dairy products, and processed foods. This study was therefore carried out...
Solid Substrate Fermentation of African Bush Mango (Irvingia gabonensis) Seeds
Aim: This study investigated the effect of fermentation on nutrient and antinutrient contents of African bush mango (Irvingia gabonensis). Methodology: Bush mango seeds were fermented for a period of five days. Microbiol...
pH Effect and pH Changes during Biocellulose Production by Gluconacetobacter xylinus in Moringa oleifera Tea-Sugar Medium
The study was carried out to determine the effect of pH and pH changes accompanying Biocellulose (BC) production by Gluconacetobacter xylinus (GX) in a Moringa oleifera tea-sugar medium. The authors adopted experimental...