Bacteriological Profile and Prevalence of ESBL and MRSA in Different Risk Categories in Diabetic Foot Infections (DFI) in a Teaching Hospital, Visakhapatnam, A.P.
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 4
Abstract
Introduction: Diabetes Mellitus (DM) is the 6th leading cause of death by 2015 and one of the leading causes of blindness, amputations and kidney failure. Our objective was to establish the variation of bacteriological profile and drug resistance prevalence, specifically extended spectrum beta lactamase (ESBL) producing gram negative bacilli (GNB) and methicillin resistant staph aureus (MRSA) among various risk categories of DFI patients to guide empirical antibiotic policy. Material and methods: In this observational study done in our teaching hospital i.e. NRIIMS, Sangivalasa village, Visakhapatnam, A.P, for 2 months (June to July 2015), we got sample size of 48 DFI Patients. Specimens were collected prior to antibiotic therapy. Culture and antibiotic sensitivity was done. Screening for MRSA and ESBL producing GNB were done. Results: Among total isolates (68), GNBs 46(68%) were predominant with a Ratio of 1:2 between GPC (22) and GNB (46). MDROs were 51(75%). In category I among 15 isolates, GNB were 10 (67%) with 7 ESBL+ve among GNB (70%). GPC were 5 (33%) with1MRSA (20%). In category II among 20 isolates 13(65%) were GNBwith10ESBL +ve (77%). Conclusion: Risk Stratification of DFI patients is the crucial step in assessing MDRO risk and selection of Right choice of empirical Antibiotic before AST report arrives.
Authors and Affiliations
V. Gayathri, Asha Rani
Keywords
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