Bacteriological Profile of Necrotising Fasciitis in A Teritary Care Centre
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 1
Abstract
Necrotising fasciitis is a potentially fatal infection that is rapidly progressive involving widespread necrosis of superficial fascia and subcutaneous tissue. It is usually associated with diabetes mellitus, trauma, Cirrhosis liver, chronic kidney disease, etc. The present study was conducted in the Department of Microbiology, Govt. Medical College, Thiruvananthapuram for a period of 1 year from May 2014 to April 2015. The objective of the study was to isolate and identify the bacterial pathogens causing Necrotising fasciitis from clinically diagnosed cases and to determine the Antibiotic susceptibility pattern of the isolates. A total number of 235 samples collected from the lesions of patients with necrotizing fasciitis admitted in the surgery wards during this period. Culture was positive in 222 samples (94.5%). Out of the total isolates, 96.5% were monomicrobial and 3.5% were poly microbial. The predominant isolate in the study was pseudomonas aeruginosa (37.44%) other isolates are Staphylococcus aureus (19.1%), Klebsiella species (11.91%), E.coli (7.65%), Streptococcus pyogenes (4.25%), Enterococci & Proteus vulgaris (3.4% each), Proteus mirabilis & CONS (2.97% each), MRSA (1.7%) and Enterobacter species (0.42%). The antibiotic sensitivity pattern of pseudomonas aeruginosa showed 100% sensitivity to Amikacin, Ceforazone – Sulbactum and Piperacillin tazobactam. Staphylococcus aureus isolates were sensitive to Cloxacilin, Amikacin and Vancomycin (100%). All the strains were resistant to penicillin. After treatment with appropriate antibiotics according to the antibiotic sensitivity pattern and surgical intervention, 204 (86.8%) patients survived. Mortality rate was 13.2% which was significantly reduced when compared to other studies because of the early treatment with appropriate antibiotics.
Authors and Affiliations
Dr Mariette Jane Pious
Keywords
Related Articles
- EP ID EP246324
- DOI -
- Views 91
- Downloads 0
Stress and Sleeping Difficulties among First Year Medical Students
Background: In recent years, there has been a growing incidence of the issues of stresses involved in medical education that can seriously affect their learning and academic performance. They may cut short their leisure...
Histopathological Spectrum of Soft tissue tumors in a rural Tertiary Care teaching hospital
Soft tissue can be defined as non epithelial extra skeletal tissue of the body exclusive of the reticuloendothelial system, glia and supporting tissue of various parenchymal organs. It is represented by the voluntary mus...
A Comparative Study of the block Characteristics of Intrathecal 0.5 Bupivacaine with and without Fentanyl as Adjuvant in Patients Undergoing Transurethral Resection of Prostate
Background: Spinal anaesthesia is a regional technique that blocks the spinal nerves in the subarachnoid space. The anaesthetic agents that are deposited subarachnoid space act on the spinal nerve roots. It is extensivel...
Case Report - Patent Urachus
The epithelial tubular structure located in the midline that spreads from the anterosuperior part of the bladder to the umbilicus is called Urachus. It connects the apex of the urinary bladder with the allantois in the f...
Seroprevalence of HIV in Women Attending Antenatal Clinic at Sultania Zanana Hospital, Gandhi Medical College Bhopal
Background: Human Immunodeficiency Virus (HIV) infection is increasing at an alarming rate globally. Apart from heterosexual route, mother to-child transmission is the next most important route of HIV transmission accoun...