Bacteriology of Diabetic Foot Ulcers with Special Reference to Antibiotic Resistance in GGH, Kakinada
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 6
Abstract
Background: Because of the altered immune status in Diabetic patients, opportunistic and infections are common in Diabetic foot ulcers. Aim: The present study was conducted to know the bacteriology and antibiogram of Diabetic foot infections in and around Kakinada and detection of ESBL producers. Material and Methods: The material for the present study was collected from patients attending OPs and those admitted in the Departments of Medicine and Surgery in Government General Hospital, Kakinada over a period of 6 months. 125 samples of pus and exudates were obtained from patients with Diabetic foot ulcers. Results: Male to female ratio observed was 2.57. The common age group affected is between 50-70 years. A total of 203 isolates were obtained from 125 cases. Staphylococcus aureus was commonest organism isolated constituting 32% of the total isolates. Pseudomonas aeruginosa was the second common organism isolated (18.4%). Coagulase Negative Staphylococci (16.8%), Klebsiella species(16.8%), Escherichia coli(8.8%), Proteus species(5.6%) and Acinetobacter species (1.6%) were the other organisms isolated. The antibiotic sensitivity testing showed Staphylococcus aureus being sensitive to Linezolid, Vancomycin, Tetracycline, Erythromycin and Cotrimoxazole. They were resistant to Penicillins, Fluoroquinolones and Cephalosporins. The Gram Negative bacilli were sensitive to Carbapenems, Betalactam & Betalactam inhibitors, Piperacillin & Tazobactam, Cephalosporins, Fluoroquinolones, Aminoglycosides and Cotrimoxazole in the decreasing order of susceptibility. All of them were resistant to Ampicillin. Of the 34 isolates of Klebsiella species, 44.11% were ESBL producers and of the 18 isolates of Escherichia coli,33.33% were ESBL producers. Conclusion: Poly-microbial infections were common in patients with Diabetic foot ulcers. it is advisable to do Antibiotic Sensitivity testing before starting treatment.
Authors and Affiliations
Dr E. Vandana Giridhar, Dr C. Lakshmi Kalavathi
Keywords
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- EP ID EP375961
- DOI 10.9790/0853-1706052731.
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