Biomarkers for Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease (COPD): What is the Role of microRNAs?
Journal Title: Pulmonary Research and Respiratory Medicine – Open Journal - Year 2015, Vol 2, Issue 4
Abstract
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous respiratory disease characterized by a progressive, not fully reversible airflow limitation associated with an abnormal inflammatory response of the lungs to noxious stimuli.1,2 Demographic data show that more than 200 million patients worldwide suffer COPD, leading the scientific community to speculate that in 2020 it will be the third important cause of mortality in the world.3 Several immune system cells (e.g. macrophages, eosinophils) and biochemical mediators (e.g. tumor necrosis factor-alpha, transforming growth factor beta, Interleukins and metalloproteases) are involved in its development and in symptoms severity.2
Authors and Affiliations
Luca Gallelli
Keywords
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- EP ID EP549977
- DOI 10.17140/PRRMOJ-2-e002
- Views 145
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