BIOTRANSFORMATION OF STEROLS BY ACTINOBACTERIA TO PRODUCE PHARMACEUTICAL PRODUCT
Journal Title: World Journal of Pharmaceutical and life sciences - Year 2017, Vol 3, Issue 4
Abstract
This review consists two parts. In the first part of review we enhance the main aim of the development of pharmaceutical industry by introducing micro biotechnological process on industrial scale and wipeout the many-level chemical coalescence. Also, this article elaborates on the current development of micro sterols biotransformation system. Actinobacteria, which has considerable importance for the production of hormonal drugs (pharmaceutical product) also has main role as a catalyst in the steroid bioconversion and the development of biotechnology. The ability to activate the transformation process of sterol substrate in a broad way, it is feasible to expect the effective use of these microorganism in the advancement of new technologies on the production of pharmaceutical steroids substrate. This article is first attempt to channelize the data on the ability of Actinobacteria to activate the distinct reaction of many biotransformation of steroid such as hydroxylation, reduction and introduction of double bonds, oxidation of steroids, reduction of hydrocarbon (ketones) and degradation, with focus on the importance of biotechnological process and analysis of steroid conversion over the last decade year. The second part of this review precisely emphasis in the location of new enzymatic approaches such as cleavage of steroid side chain.
Authors and Affiliations
Dr. Sikander Ali
Keywords
Related Articles
- EP ID EP649075
- DOI -
- Views 183
- Downloads 0
EFFECT OF DIFFERENT CONCENTRATION OF TABLE SALT AND IODINE TREATED SALT AGAINST 3RD AND 4TH INSTARS AEDES AEGYPTI AND AEDES ALBOPICTUS LARVAE IN LABORATORY
The present study aimed to evaluate the larvicidal activity of different concentration of table salt and iodine salt on laboratory reared Aedes aegypti larvae from Dagon Myothit North Townships in Yangon Region from May...
AKSHOTAKA HERB USED IN ANCIENT INDIAN MEDICINE- LITERARY AND PHARMACOLOGICAL REVIEW
The traditional Indian system of medicines like Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homeopathy mainly uses medicinal plants for the management of diseases. As herbal products are natural products and are sa...
ESTIMATION OF VARIATION IN THE PROPORTION OF VIRIDANS POPULATION IN SALIVA OF HEALTHY AND CARIOUS INDIVIDUALS
Background: Oral cavity is colonized by many bacterial species, fungi and parasites. Though all these organisms are present in the oral cavity and are considered to be commensals, most of them are opportunistic. Some of...
FORMULATION AND EVALUTION OF TWO IN ONE HERBAL CONDITIONING SHAMPOO CONTAINING EXTRACT OF ALLIUM CEPA AND TRIGONELLA FOENUM GRAECUM
Shampooing and conditioner is the most common form of hair treatment. The primary function of shampoo is cleansing of the hair and the conditioner is used as a hair tonic. We formulated onion and fenugreek two in one her...
E- CIGARETTE: A REVIEW
An electronic cigarette (E-cigarette) is handheld electronic device, which vaporizes the flavored liquid called e – liquid, consists of nicotine, propylene glycol, glycerin and flavorings. Person inhales this vapor calle...