BISPHOSPHONATE THERAPY AND JAW OSTEONECROSIS: AN OVERVIEW
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 8
Abstract
BACKGROUND Bisphosphonates are anti-resorptive agents that have been used for more than a decade, for the treatment of metabolic bone diseases, such as osteoporosis and osteopenia, and to control the skeletal complications associated with metastatic bone disease. Despite their proven efficacy as anti-resorptive drugs, a devastating side-effect, ‘Bisphosphonate Related Osteonecrosis of the Jaws’ (BRONJ), has been documented over the last decade. This article aims to provide an overview of bisphosphonates and BRONJ, to improve the awareness among practitioners.
Authors and Affiliations
Shalini Krishnan, Gogineni Subhas Babu, Rajeev T. P
DEATH DUE TO CHOKING IN AN ELDERLY PSYCHIATRIC PATIENTA CASE REPORT
Choking is a form of asphyxial death in which there is blockage of internal airways. Mostly it is either accidental or homicidal. In accidental choking, the airways are usually blocked by a large food bolus or some forei...
COMPARE THE EFFICACY AND SAFETY OF COMBINED SUPERFICIAL AND DEEP CERVICAL PLEXUS BLOCK IN CAROTID ENDARTERECTOMY PATIENTS USING ULTRASOUND GUIDANCE AND LANDMARK TECHNIQUE WITH THE GENERAL ANAESTHESIA TECHNIQUE
BACKGROUND Carotid endarterectomy remains the gold standard in both symptomatic and asymptomatic carotid artery occlusive disease1 which can be performed either under general anaesthesia or regional anaesthesia using ult...
ESTIMATION OF pH, TOTAL ACID AND ETHANOL CONTENT OF COMMERCIALLY AVAILABLE ALCOHOL-CONTAINING MOUTHWASHES AND ITS EFFECT ON SALIVARY pH
BACKGROUND Use of mouthwash has become widespread as a part of routine oral hygiene. Mouthwashes may have deleterious effects on oral tissues because of its low pH, high acid content and use of ethanol as an antiseptic a...
DOPPLER STUDY IN HIGH-RISK PREGNANCIES IN THIRD TRIMESTER OF PREGNANCIES FOR PREDICTION OF ADVERSE PERINATAL OUTCOME
BACKGROUND Our study aimed to evaluate the Doppler value in third trimester of pregnancy where the features at risk is suspected. The patient with abnormal findings are identified and intervened for timely confinement. A...
SPECTRUM OF VITAMIN D IN TYPE 2 DIABETES MELLITUS: A HOSPITAL BASED STUDY
BACKGROUND Vitamin D deficiency has been found to have an inverse relationship with the occurrence of type-2 diabetes mellitus. The aim of this study was to assess serum vitamin D level in patients with type 2 DM and cor...