Blood donors screening for blood born viruses in Poland
Journal Title: Przegląd Epidemiologiczny - Year 2015, Vol 69, Issue 3
Abstract
Blood donor screening of viral markers in Poland is based on serologic testing for anti-HCV, HBsAg, anti- HIV1/2 (chemiluminescence tests) and on nucleic acid testing (NAT) for RNA HCV, RNA HIV-1 and DNA HBV performed in minipools of 6 with real-time PCR (MPX 2.0 test on cobas s201) or with TMA in individual donations (Ultrio Plus or Ultrio Elite). Donors of plasma for anti-D and anti-HBs production are tested for parvovirus B19 DNA. Before implementation tests and equipment are evaluated at the Institute of Hematology and Transfusion Medicine (IHTM). The last 20 years witnessed a decreasing trend for HBsAg in both first time and repeat donors (1% - 0.3% and 0.1% - 0.02% respectively). Prevalence of anti-HCV repeat reactive results was stable and oscillated around 0.8% for first time donors and 0.2% for repeat donors. Elevated prevalence of seropositive HIV infected donors was recently observed (7.5-9 cases/100,000 donors). Since respective molecular markers implementation HCV RNA was detected on average in 1/119,235 seronegative donations, HIV RNA in 1/783,821 and HBV DNA in 1/61,047. HBV NAT yields were mostly occult hepatitis B (1/80,248); window period cases were less frequent (1/255,146). The efficiency of HBV DNA detection depends on the sensitivity of the HBV DNA screening system.
Authors and Affiliations
Piotr Grabarczyk, Aneta Kopacz, Ewa Sulkowska, Dorota Kubicka-Russel, Maria Mikulska, Magdalena Łętowska
The analysis of the occurrence of nosocomial infections in the neurosurgical ward in the District Hospital from 2003-2012
INTRODUCTION. The patients in the neurosurgical ward are exposed to many risk factors causing nosocomial infections. These factors are related to operations, invasive diagnosing and monitoring of the nervous system and m...
Epidemiologia zakażeń HCV w Europie Środkowej i Południowo-Wschodniej
CELEM PRACY jest oszacowanie rozpowszechnienia zakażeń HCV w 14 krajach Europy Środkowej i Wschodniej. MATERIAŁ I METODY. W pracy zaprezentowano dane porównawcze dotyczące osób, u których wykryto obecność przeciwciał ant...
What mother know about vaccine preventable diseases? / Co wiedzą matki na temat chorób zakaźnych, którym można zapobiegać poprzez szczepienia?
INTRODUCTION AND OBJECTIVE: The improving epidemiological situation of the most of communicable diseases causes, that the real and potential risks attributable to them have been forgotten. The aim of study was to determi...
Occurrence and clinical characteristics of hepatocellular carcinoma in the north-eastern Poland / Występowanie i cechy kliniczne raka wątrobowokomórkowego wśród chorych z regionu północno-wschodniej Polski
Hepatocellular carcinoma (HCC) is the fifth most common malignancy and the third leading cause of cancerrelated mortality worldwide. Risk factors for this malignancy include liver cirrhosis, HBV or HCV infection, fatty l...
Evaluation of human papilloma virus (HPV) vaccination strategies and vaccination coverage in adolescents girls worldwide
STUDY OBJECTIVE. An analysis of HPV vaccination strategies and vaccination coverage in adolescent girls worldwide for the last eight years with regard to potential improvement of vaccination coverage rates in Poland. MET...