Blood Group Distribution and Its Relationship with Bleeding Time and Clotting Time in Medical Undergraduate Students
Journal Title: International Journal of Research and Review - Year 2017, Vol 4, Issue 9
Abstract
Background: In 1901 an Austrian scientist Karl Landsteiner, discovered the ABO blood group in human. Blood group plays a vital role in the field of transfusion medicine. The previous studies found prolonged bleeding and clotting time in individuals with blood group O probably due to lower expression of von Willebrand factor, and elevated levels are risk for thrombosis. Aims and Objectives: The objective of the study was to assess the relationship between bleeding time and clotting time among various blood groups and to identify gender difference between them. Materials and methods: Our study included 100 medical undergraduates, aged between 17–22 years. The blood grouping was determined with the standard antisera and bleeding time and clotting time was estimated by duke method and capillary tube method respectively. Results: Blood group O (33%) was more predominant among students followed by blood group A (32%), B (26%) and AB (9%). Bleeding time was found to be prolonged > 4 min in blood group O (21.21%), followed by blood group B (19.23%), A (18.75%) and AB (11.11%) but the difference was statistically insignificant (p = 0.867). Similarly clotting time was prolong > 6 min among blood group A (15.63%) followed by O (6.07%), B (3.84%) and AB (0%) but the difference was statistically insignificant (p = 0.192).Gender-wise bleeding time and clotting time were more prolonged in females than males. Conclusions: In our study, blood group O was most predominant. Bleeding time was prolonged in blood group O whereas clotting time was prolonged in blood group A. Gender-wise bleeding and clotting time were higher in females than males.
Authors and Affiliations
Jha RK
Keywords
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