BMI in patients with obstructive sleep apnea
Journal Title: Current Issues in Pharmacy and Medical Sciences - Year 2015, Vol 28, Issue 4
Abstract
Obstructive sleep apnea (OSA) is a disease of multicasual etiology. The risk factors include obesity, among other issues. Hence, it is extremely important to determine the effect of body weight on the severity of OSA. The aim of the study was to evaluate the influence of the body weight expressed as body mass index (BMI), on the value of upper airways diameter and on the AHI (Apnea-Hypopnea Index) value. The study was comprised of 41 patients diagnosed with OSA by way of polysomnography. Each patient was first examine via a lateral cephalometric image of the skull, which served to measure the upper and lower diameter of the upper airways. BMI was also calculated for each patient. Statistical analysis was carried out in accordance with Pearson's correlation coefficient test. Our work demonstrated a negative correlation between BMI and the diameter of the upper airways, and a positive correlation between BMI and AHI value. We thus put forward that the increase in body weight in patients with OSA can contribute to the severity of the disease, regardless of the fact that it may not lead to a reduction of the lumen of the upper airways.
Authors and Affiliations
Magdalena Dobrowolska-Zarzycka, Izabella Dunin-Wilczynska, Iwona Mitura, Jolanta Szymańska
Keywords
Related Articles
- EP ID EP101728
- DOI 10.1515/cipms-2015-0080
- Views 97
- Downloads 0
The influence of the eutectic mixtures: salicylic acid – menthol and benzocaine – menthol on physical properties of the creams with fluconazole
Fluconazole is used in treatment of the surface mycoses of the skin. Menthol, salicylic acid and benzocaine are the components of many preparations for topical use. When mixed they form the eutectic mixtures. The purpose...
TLC-densitometric analysis of α-escin in bulk drug substance and in pharmaceutical dosage forms
A quite simple and rapid TLC-densitometric method for the identification of α-escin (Aescin) in bulk drug substances was developed. In so doing, different chromatographic conditions, including various mobile and stationa...
Dissolution of lithium carbonate from three types extended-release capsules in paddle, basket and flow-through apparatus
Current Issues in Pharmacy and Medical Sciences Vol. 25, No. 2, Pages 164-167 Three types of 24-h extended-release multiparticulate capsules containing a dose of 480-504 mg lithium carbonate in a form of either pellets...
The international normalized ratio (INR) as seen in a population of patients with atrial fibrillation and cerebral infarction undergoing long-term treatment with vitamin K antagonists
It is estimated that nearly 20% of all cerebral infarctions in the total population are the result of a complication of atrial fibrillation (AF). While oral anticoagulation with vitamin K antagonists (AVKs) substantially...
Specifics of proximal caries and their diagnostics in posterior teeth
Proximal surfaces are the second in turn after the occlusal surfaces, as being the most exposed places to the carious process. The specificity of changes and location makes the diagnostic of approximal cavities difficult...