Bone mineral density in obese children with prediabetes
Journal Title: Ege Tıp Dergisi - Year 2018, Vol 57, Issue 2
Abstract
Aim: The aim of this study was to evaluate the relationships between bone mineral density (BMD) vs metabolic risk factors in obese adolescents with prediabetes. Materials and Methods: A total of 131 obese children and adolescents, aged 6-18 years of age were enrolled the study. Prediabetes was determined by a fasting blood glucose level of ≥100 to 125 mg/dL or 2-hour oral glucose tolerance test value of ≥140 to 199 mg/dL. Five patients who were diagnosed as having type 2 diabetes were excluded and remaining participants were classified as normal glucose tolerance (NGT) and prediabetic. BMD was measured on calcaneus using quantitative ultrasound. BMD and metabolic parameters were investigated and compared in these two groups. Results: There was no significant difference in BMD between children and adolescents with prediabetes (n=37) or NGT (n=89). The parameters of prediabetes did not affect BMD and these results did not change when we adjusted for weight, height, age, sex, pubertal status. The multivariate linear regression analysis revealed that the only independent factor associated with higher BMD was higher body mass index (BMI) (OR=0.007, 95%CI: 0.002-0.013, p=0.013). No significant associations were found between BMD and waist circumference or biochemical measurements. Conclusion: Plasma glucose within the prediabetic range is not associated with bone mineral density in obese children. Thus, the positive association of BMI with BMD may be by means of alternative pathways.
Authors and Affiliations
Ala Üstyol, Mehmet Emre Atabek
Keywords
Related Articles
- EP ID EP459929
- DOI -
- Views 91
- Downloads 0
Examination of attitudes and success levels of dentistry students towards biostatistics course
Aim: Biostatistics is of great significance for practices and research designs in dentistry to analyze data, to interpret the results and to publish high quality publications. This study conducted to assess the success a...
The functional dependency rates of Bornova district residents over age 65
Aim: The elderly populations of societies are increasing proportionately as a result of increased life expectancy. The increase in the elderly population is important in shaping the health and social policies of society....
Tracheal intubatı̇on wı̇thout muscle relaxants in chı̇ldren
Aim: Tracheal intubation without muscle relaxants is usually performed with alfentanil and propofol or sevoflurane. Alfentanil 5 to 40 μg/kg, propofol 2.0-4.0 mg/kg sevoflurane up to 1 MAC provide excellent or good intub...
Determination of the association between the C677T and A1298C polymorphisms of the MTHFR gene and the development risk of azoospermia and oligozoospermia in Turkish infertile men
Aim: We aimed to investigate the relationship between unexplained male infertility, and the -677C/T (rs1801133) and -1298A/C (rs1801131) polymorphisms of the MTHFR gene in a group of Turkish infertile men with non-obstru...
Knowledge and behavior of coiffeur employees about hepatitis in Aksaray city center
Aim: Taking the hepatitis B and hepatitis C prevalence in Turkey into account, the coiffeur employees may play a role in the spread of these diseases and our study aimed to determine the knowledge level and practices of...