Bone mineral density in obese children with prediabetes
Journal Title: Ege Tıp Dergisi - Year 2018, Vol 57, Issue 2
Abstract
Aim: The aim of this study was to evaluate the relationships between bone mineral density (BMD) vs metabolic risk factors in obese adolescents with prediabetes. Materials and Methods: A total of 131 obese children and adolescents, aged 6-18 years of age were enrolled the study. Prediabetes was determined by a fasting blood glucose level of ≥100 to 125 mg/dL or 2-hour oral glucose tolerance test value of ≥140 to 199 mg/dL. Five patients who were diagnosed as having type 2 diabetes were excluded and remaining participants were classified as normal glucose tolerance (NGT) and prediabetic. BMD was measured on calcaneus using quantitative ultrasound. BMD and metabolic parameters were investigated and compared in these two groups. Results: There was no significant difference in BMD between children and adolescents with prediabetes (n=37) or NGT (n=89). The parameters of prediabetes did not affect BMD and these results did not change when we adjusted for weight, height, age, sex, pubertal status. The multivariate linear regression analysis revealed that the only independent factor associated with higher BMD was higher body mass index (BMI) (OR=0.007, 95%CI: 0.002-0.013, p=0.013). No significant associations were found between BMD and waist circumference or biochemical measurements. Conclusion: Plasma glucose within the prediabetic range is not associated with bone mineral density in obese children. Thus, the positive association of BMI with BMD may be by means of alternative pathways.
Authors and Affiliations
Ala Üstyol, Mehmet Emre Atabek
Keywords
Related Articles
- EP ID EP459929
- DOI -
- Views 100
- Downloads 0
Evaluation of risky behaviors among adolescents admitted to a research and training hospital
Aim: Adolescence is a period when physical, psychological and social changes occur that could form the essentials of a long and healthy life. The risky behaviors that adolescents attain during this period can continue in...
Nasal myiasis in a patient hospitalized at Ege University Hospital
Myiasis is an infestation caused by Dipterous fly maggots various organs and tissues of animals or humans. It receives the name of the affected organ. Nasal myiasis is mostly caused by Sarcophagidae and Calliphoridae fam...
A case of idiopathic hypoparathyroidism presenting with spondyloarthropathy
Idiopathic hypoparathyroidism is a rarely seen endocrinopathy characterized by insufficient parathyroid hormone secrection. It is manifested by hypocalcemia, hyperphosphatemia and lower parathyroid hormone level. Widespr...
Co-existence of celiac disease and eosinophilic esophagitis: Is it a coincidence for the two diseases?
Celiac disease and eosinophilic esophagitis are usually considered to be separate gastrointestinal diseases; however, it appears that they may coexist more often than would be expected. We report the case of a 5-year-old...
Complex regional pain syndrome type 1 in a child
Complex regional pain syndrome type 1 (CRPS 1), formerly known as reflex sympathetic dystrophy (RSD), is characterized by pain, sensory and vasomotor disturbances, trophic changes and impaired motor function. The pathoge...