Botanical Study and evaluation of the antifungal activity of the 70% ethanolic extract of HunteriaeburneaPichon (Apocynaceae)
Journal Title: Scholars Academic Journal of Biosciences - Year 2017, Vol 5, Issue 3
Abstract
In developing countries infectious diseases constitut a public health concern. The objective of this study is to assers the antifungal activity of the stem bark of Hunteriaeburnea, a medicinal plant frequently used in several therapeutic formuli in the region of Haut Sassandra (Ivory Coast) against microbial diseases. An ethnobotanical survey in the region of Haut Sassandra allowed us to select Hunteriaeburnea, one of the most used species in the treatment of skin diseases. In order to learn more about this plant and identify it well on the field, we have, in this study, made its botanical description and an evaluation of its antifungal activity against Candidaalbicans, Cryptococcusneoformans and Trichophytonmentagrophytes. This study shows that Hunteriaeburnea has an in vitro antifungal activity against Cryptococcusneoformans (MFC = 6.25 mg/mL), Candidaalbicans (MFC = 25 mg/mL) and Trichophytonmentagrophytes (MFC = 3.12 mg/mL). Trichophytonmentagrophytes with (MFC = 3.12 mg/mL; IC50 = 0.5 mg/mL) is the most sensitive fungal germs with 70 % ethanolic extract of the stem bark of Hunteriaeburnea, which justifies the use of its bark in traditional environment.
Authors and Affiliations
Yao Kanga, Irié Otis Tra Bi, Kouadio Bené, NoelZirihi G
Keywords
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