BRAINSTEM AUDITORY EVOKED POTENTIAL AS AN INDEX OF CNS DEMYELINATION IN GUILLAIN -BARRÉ SYNDROME (GBS)
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2016, Vol 5, Issue 1
Abstract
Background: Guillain-Barré Syndrome (GBS) is an acute, frequently severe and fulminant polyradicular neuropathy that is autoimmune in nature. GBS manifest as rapidly evolving areflexic motor paralysis with or without sensory disturbances. It mainly involves peripheral nervous system and autonomic nervous system. There are rare evidences about the involvement of central nervous system (CNS) in GBS. Aims: The main objective of the study was to assess the CNS involvement in GBS using the Brainstem Auditory Evoked Potential (BAEP). Methods & Material: The study was conducted in the clinical neurophysiology lab in the department of physiology, CSMMU Lucknow. Study group involved 26 subjects (n=26) having GBS and control group involved 30 normal subjects (n=30). BAEPS were recorded by Neuroperfect- EMG 2000 EMG/NCV/EPsytem. The data so obtained were subjected to analysis using Statistical Package for Social Sciences (SPSS) Version 13.0. Results & Conclusions: There was significant increase in PIII & PV peak latencies and PI-PIII & PI-PV interpeak latencies in both left and right ear in the study group, which showed the CNS involvement in GBS which can be assessed using BAEP.
Authors and Affiliations
Smita Singh| Associate Professor, Department of Physiology, Mayo Institute of Medical sciences, Barabanki, Dr. Nitesh Mishra| Assistant Professor, Department of Physiology, Meenakshi Medical College & RI, Kanchipuram, Email: nitesh_rbl@rediffmail.com, Dr. Shraddha Singh| Professor, Department of Physiology, Chatrapati Shahuji Maharaj Medical College, Lucknow, Dr. SunitaTiwari| Professor & HOD, Department of Physiology, Chatrapati Shahuji Maharaj Medical College, Lucknow
Keywords
Related Articles
- EP ID EP11556
- DOI 10.5958/2319-5886.2016.00002.3
- Views 279
- Downloads 9
Effect of Kinesio Taping on Motion, Pain with Functional Performance and Subsequent Quality of Life in Subject with Subacromial Impingement Syndrome
Background: This study examined the response of kinesio taping (KT) in combination with the conventional occupational therapy as compared to conventional occupational therapy alone on motion, pain with functional perfo...
Smoking Pattern and Determinants among Adults Attending Anti-Smoking Clinic in Aseer Region, Saudi Arabia
Objective: To evaluate smoking pattern and associated factors related to smoking for patients attending anti-smoking clinic in Aseer region, Saudi Arabia. Methods: A Cross-sectional study design used to carry out this r...
Dialysis Modality Preferences and Quality of Life of Adolescents with Renal Failure
The present research explored the differences in perceived quality of life of adolescents afflicted with End stage renal disease (ESRD)/ renal failure with reference to different dialysis modality. It was hypothesized t...
Anaesthetic Management of a Case with Congenital Complete Heart Block Posted for Lower Segment Caesarean Section
Complete heart block in pregnancy is relatively a rare problem. It may be congenital or acquired. Congenital complete heart block may be asymptomatic. Acquired causes may be secondary to cardiac surgery, rheumatic heart...
PREVALENCE OF HEALTH CARE ASSOCIATED INFECTIONS IN A TERTIARY CARE HOSPITAL IN DAKSHINA KANNADA, KARNATAKA: A HOSPITAL BASED CROSS SECTIONAL STUDY
Background: Health Care-Associated Infections (HCAI) affect millions of people each year and raise a great risk for patients in health care settings, leading to high rates of morbidity and mortality. Objective: To estim...