BRIEF REVIEW ON MULTIPLE SCLEROSIS
Journal Title: World Journal of Pharmaceutical Research - Year 2017, Vol 6, Issue 11
Abstract
There is no known cure for multiple sclerosis. Treatments attempt to improve function after an attack and prevent new attacks. Medications used to treat MS, while modestly effective, can have side effects and be poorly tolerated Multiple sclerosis usually starts with an acute episode of neurological disturbance, termed a 'clinically isolated syndrome', followed by an illness phase punctuated by relapses and remissions which may transition after 10 years to a phase of progressive accumulation of disability without relapses. Fifteen to 20% of patients will have a progressive course from the onset. There is significant interpatient variability in prognosis. The main diagnostic criteria are clinical, supported by investigations including magnetic resonance imaging and lumbar puncture and evoked potentials. First line disease modifying agents for relapsing remitting multiple sclerosis include interferon-ß and glatiramer. First line treatment for relapses is usually intravenous methylprednisolone for 3 days. Troublesome symptoms may include spasticity, parasthesias, tremor, erectile dysfunction, depression and anxiety, fatigue and pain. After excluding differential diagnoses, symptomatic management includes pharmacological agents, allied health consultation and continence strategies. Although pregnancy reduces disease activity, there is a higher risk of relapse in the postpartum period.
Authors and Affiliations
Deepak Bhatt
Keywords
Related Articles
- EP ID EP618243
- DOI -
- Views 175
- Downloads 0
EFFECTS OF HONEY SUPPLEMENTATION ON CHILDREN WITH IDIOPATHIC DILATED CARDIOMYOPATHY: A RANDOMIZED SINGLE BLINDED CONTROLLED STUDY
Objectives: Evaluation of the effects of 12-weeks honey consumption on the echocardiographic parameters of children with idiopathic dilated cardiomyopathy (IDCM). Design: This study was a randomized controlled study, whi...
ANCIENT CONCEPTS OF COSMETOLOGY IN AYURVEDA
The word cosmetics defined as substances of diverse origin, scientifically compounded and use to Cleanse, Allay skin troubles, Cover up imperfection and Beauty. In ancient India, many of these practices were subtly inter...
ALOE VERA GEL REVERSES HAEMOSTATIC DERANGEMENT IN RATS FOLLOWING SALT LOADING.
This research investigated the effect of Aloe vera (gel) on haemostatic status of high salt loaded rats. Twenty wistar rats (200-250g) were randomly assigned into 4 groups (n=5) thus: control, Aloe (600mg/kg of Aloe vera...
“A LITERARY REVIEW ON PAEDIATRIC CONSTIPATION W.S.R TO ORGANIC PATHOLOGY, ITS DIAGNOSIS AND MANAGEMENT.”
Constipation is a severe concern in day today outpatient and indoor admission in infant and young children. The evaluation of constipation involves first determining whether the change in the frequency or consistency of...
SYNTHESIS AND ANTI CONVULSANT ACTIVITY OF SOME TRAIZOLE DERIVATIVES
Compounds with 1, 2, 4-triazole moiety found to display a wide range of potent biological activities such as antifungal, anti-inflammatory, anticonvulsant, antimicrobial and anti tumor activity. In the present scheme, we...