BUCCAL BIOADHESIVE DRUG DELIVERY –A PROMISING OPTION FOR CONVENTIONAL THERAPY
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2019, Vol 6, Issue 11
Abstract
Since, the last four decades, the concept of mucoadhesion has achieved a much valuable interest in the various fields of pharmaceutics. There are many advantages of mucoadhesive buccal drug delivery system that made this a novel drug delivery system for the local as well as systemic delivery of various drugs. The main advantage of this drug delivery system is that it prolongs the residence time of the dosage form at the site of application. Due to the high blood supply and relatively high permeability of the buccal mucosa, the buccal cavity is the best option for both local as well as systemic delivery of various drugs. This review concludes that the mucoadhesive drug delivery system was found to be a better alternative to the conventional oral route. It is a unique alternative to conventional drugs by virtue of its ability in overcoming hepatic metabolism, reduction in dose, frequencies and enhancing bioavailability. This delivery system will shows a controlled release of drug; ease of application and the formulation and evaluation of such systems does not have any complication. So we can expect that the mucoadhesive system may be one of the important dosage form in the future pharmaceutical and health care sector.
Authors and Affiliations
V. M. Vaidya
Keywords
Related Articles
- EP ID EP672380
- DOI -
- Views 233
- Downloads 0
ANTIMALARIAL PHENOLIC COMPOUNDS IN AFRICA: A REVIEW
Malaria is currently a public health problem due to many factors such as parasite resistance, mosquito vector resistance, non-availability of vaccine and adverse reactions of antimalarial drugs. Traditional herbal medici...
CHANGES IN PLATELET AND PLATELET INDICES DURING PREGNANCY AS POTENTIAL MARKERS FOR PREDICTION OF PREECLAMPSIA DEVELOPMENT, 2016
Background: Platelets, also called thrombocytes, are a component of blood whose function (along with the coagulation factors) is to stop bleeding by clumping and clotting blood vessel injuries. Preeclampsia is a conditio...
HEMATOLOGICAL CHANGES IN DRUGS ABUSERS ATTENDING TO ABDELAAL ELIDRESI PSYCHIATRIC HOSPITAL
Background: Complete blood count (CBC) is a blood test used to evaluate your overall health and detect a wide range of disorder including anemia, infection and leukemia, Drugs are chemicals structures it is different typ...
ANTIAMNESIC EFFECT OF PRUNUS CERASUS FRUIT EXTRACT (CHERRY) OF NICOTINE – INDUCED MEMORY AND COGNITIVE IMPAIRMENT IN WISTAR RATS
Antiamnesic effect of Prunus Cerasus fruit extract of nicotine-induced memory and cognitive impairment in wistar rat was studied. 40 wistar rats of similar weight were randomly divided into 8 group as follows; Group 1 co...
CORRELATION BETWEEN SEMINAL FLUID ANALYSIS AND LEVEL OF FSH, PROLACTIN AND TESTOSTERONE IN SUDANESE INFERTILE PATIENTS
Background: Infertility, defined as the inability to conceive after at least one year of unprotected intercourse. The management of infertility problems has become an increasingly important part of health services during...