Cardiac Effect of Interstitial Lung Disease Correlated with Spirometry and Six Minute Walk Test
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 2
Abstract
Introduction: The cardiac effect of different pulmonary functions, six minute walk distance, arterial blood gases and saturation in Interstitial Lung Disease (ILD) is not much known. So this study, a tertiary care hospital experience that entails to know the various factors in Pulmonary Hypertension (PH) mentioned above causing PH and their correlation with PH. Aim: To study the correlation of PH in patients with ILD with spirometry and six minute walk test (6MWT) Materials and Methods: All consecutive patients with confirmed diagnosis of ILD taken over a period of 1½year in tertiary care hospital. 6MWT and spirometry were performed as per the American Thoracic Guidelines. Percent predicted 6 minute walk distance was calculated using Enright et al., and Indian reference equation. PH was diagnosed using 2-D echo. The spirometry variables and 6MWT were then correlated with the mean pulmonary artery pressure. Results: There were 75 patients. About 66.66 % had PH on 2-D echo. The mean% predicted six minute walk distance as per the Indian reference equation, pre- and post- exercise PaO2 as well as desaturation had a significant correlation with PH. Spirometry variables Forced Expiratory Volume in First Second (FEV1) and Forced Vital Capacity (FVC) did not correlate with PH. Conclusion: Thus, the 6MWT correlated significantly with PH while spirometry did not.
Authors and Affiliations
Mitali Bharat Agrawal, Nilkanth Tukaram Awad
Keywords
Related Articles
- EP ID EP332741
- DOI 10.7860/JCDR/2017/21357.9292
- Views 140
- Downloads 0
A Rare Collision Tumour of UterusSquamous Cell Carcinoma and Endometrial Stromal Sarcoma
Collision tumours are defined by co-existence of two tumours in the same or adjacent organs which are topographically and histologically distinct with minimal or no histological admixture. Collision tumours have been des...
A Case of Janumet Poisoning
Janumet, an anti-diabetic drug is being increasingly used. Each tablet contains 50 mg of sitagliptin + 500/1000 mg of metformin. Metformin works by decreasing glucose production in the liver and decreasing absorption of...
The Role of Epidermal Growth Factor Receptor in Cancer and their Application for New Targeted Cancer Therapy
ABSTRACT Epidermal Growth Factor Receptor (EGFR) has central role in cancer therapy because it causes tumour progression in many cases. The EGFR has seven ligands. Each factor that can block this binding, inhibits the in...
Practice of Intravenous to Oral Conversion of Antibiotics and its Influence on Length of Stay at a Tertiary Care Hospital: A Prospective Study
ABSTRACT Introduction: Several studies have demonstrated the efficacy and safety of switching from intravenous to oral antibiotics in clinically stable patients. Early switch from Intravenous (IV) to Per Oral (PO) could...
Polymorphism in the Eruption Sequence of Primary Dentition: A Cross-sectional Study
Introduction: Primary teeth have shown wide variations in their eruption time among different population. Population specific eruption ages are provided as mean with standard deviations or median ages with its percentile...