Cardio-renal association
Journal Title: Journal of Analytical Bio-Science - Year 2012, Vol 35, Issue 3
Abstract
The cardio-renal association includes the widely known relationship between kidney function and cardiovascular disease (CVD). The interaction between renal and cardiac functions is very important for regulatory functions and hemodynamic control. Therefore, understanding these two important systems is crucial to improving the management of patients with cardio-renal disease. The relationship between the heart and kidneys occurs at multiple levels, including the rennin-angiotensin system, the sympathetic nervous system, and natriuretic peptides. Chronic kidney disease (CKD) and CVD share similar etiologic risk factors, including hypertension, dyslipidemia, diabetes mellitus, smoking, and obesity. The majority of vascular events are caused by accelerated atherosclerosis. If these factors are controlled, then atherosclerotic process evolution, and further target-organ damage or cardiovascular events can be prevented. Therefore, prevention can be carried out not just at the first stage but along the whole continuum. CKD is a novel risk factor included at this stage that accelerates both vascular and cardiac damage.
Authors and Affiliations
Shunji Namba
Keywords
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