Carotenoid production by Rhodotorula mucilaginosa UIMC35 and investigation of its antifungal effect on Aspergillus fumigatus, Aspergillus flavus and Mucor hiemalis
Journal Title: مجله علمی- پژوهشی دانشگاه علوم پزشکی قم - Year 2017, Vol 11, Issue 8
Abstract
Background and Objectives: Carotenoids are an important group of natural pigments with specific applications as colorants, food supplements, and additives; they are also used in medicine, cosmetics, and biotechnological purposes. In this study, carotenoid production by Rhodotorula mucilaginosa UIMC35 and its antifungal effect on Aspergillus fumigatus, Aspergillus flavus, and Mucor hiemalis, were investigated. Methods: In this semi-experimental research, yeast was isolated from different natural sources and identified by macroscopic, microscopic, and biochemical tests. Then, yeast strain was identified using PCR technique. Carotenoids were extracted from the yeast strain by Davis method. After 48 hours, antifungal activity of the carotenoid, was determined against mold fungi according to growth inhibition percentage. The results were analyzed using estimated Kruskal-Wallis test. Results: In this study, the isolated yeast strain was Rhodotorula mucilaginosa UIMC35. Growth inhibition percentage of Aspergillus fumigatus, Aspergillus flavus, and Mucor hiemalis, by Rhodotorula mucilaginosa UIMC35 carotenoids was determined to be 76.19, 66.67, and 21.05, respectively. Conclusion: According to the results of this study, Rhodotorula mucilaginosa UIMC35 isolated from soil in Isfahan, could produce high potency carotenoids and the extracted pigment had a significant inhibitory effect against the studied mold fungi. Therefore, further researches can provide the possibility of using Rhodotorula yeast in various fields, such as pharmacy, food Industry, and cosmetics.
Authors and Affiliations
Bahareh Mohammadi, Mahboobeh Madani, Ali Mohammad Ahadi
Keywords
Related Articles
- EP ID EP479006
- DOI -
- Views 39
- Downloads 0
The Effectiveness of Neurocognitive Rehabilitation On the Math Performance and Working Memory of Students with Dyscalculia
Background and Objectives: Cognitive functions are one of the most important effective factors in students with dyscalculia. The present research aims to investigate the effectiveness of neurocognitive rehabilitation pro...
Investigation of Survival Rate among HIV-Positive Individuals Identified in Isfahan Province, 1997-2013 (IRAN)
Background and Objectives: AIDS is one of the most important causes of death among adults. The effect of prognostic factors on HIV-positive patients has not been properly investigated, but it can be estimated by retrospe...
اثرات ارکیدکتومی بر سطح سرمی هورمون‌های TSH، T3 وT4 در موش‌های صحرایی نر
زمینه و هدف: بررسی‌ها نشان داده‌اند تغییر سطح سرمی هورمون‌های جنسی می‌تواند عملکرد غده تیروئید را تحت تأثیر قرار دهد. هدف از این مطالعه بررسی اثر کاهش تستوسترون پس از انجام ارکیدکتومی بر سطح سرمی هورمون‌های تیروئیدی در م...
Biosorption of Bisphenol A by Agricultural Waste: A Kinetic and Isothermic Study
B Abstract Background and Objectives: Bisphenol A is a phenolic compound, which even in low concentration, is harmful and toxic for human and environment and is abundantly found in industrial effluents. In the present...
جذب زیستی بیس‌فنل A توسط زائدات کشاورزی: بررسی ایزوترمی و سینتیکی
زمینه و هدف: بیس‌فنل Aاز ترکیبات فنل می‌باشد که حتی در غلظت‌های بسیار کم برای انسان و محیط زیست، خطرناک و سمّی بوده و در فاضلاب‌های صنعتی به فراوانی یافت می‌‌شود. در مطالعه حاضر، حذف بیس‌فنل A به‌وسیله زائدات گیاه کلزا...