CAROTID INTIMA MEDIA THICKNESS IN PATIENTS WITH ACUTE ISCHAEMIC STROKE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 7
Abstract
BACKGROUND Carotid intima media thickness reflects ongoing atherosclerosis in the body and can be measured by B-mode ultrasound. It is found to be a risk factor for cardiovascular diseases. Our study intends to find association of carotid intima media thickness with acute ischaemic stroke. Objectives- To study the association between common carotid artery intima media thickness in patients with acute ischaemic stroke. To study the pattern between carotid intima media thickness and subtypes of ischaemic stroke. To study the pattern between carotid intima media thickness and size of infarct. MATERIALS AND METHODS The study design was a case control study. After getting ethical clearance, 42 cases and 42 controls satisfying the inclusion criteria were enrolled in the study. The data on demographic characteristics, smoking and cardiovascular risk factors were collected as a structured questionnaire. B Mode ultrasound Doppler of both common carotid arteries with carotid intima media thickness measurement was done for all participants in the study. Data analysis was done by SPSS software. Tests of significance were done to find association between CIMT and acute ischaemic stroke, subtypes of brain infarction, while scattered plot for assessing size of infarct. RESULTS Carotid plaques were present in 40.5% of cases and 14.3% of controls. The mean carotid intima media thickness in the present study is 0.90 ± 0.1 among cases and 0.80 ± 0.1 among controls (p= 0.001). The risk for stroke was 57.1% among cases and 23.8% among controls (p= 0.002). Among infarct subtypes 52.3% had PACIs, 23.8% had LACIs, 16.6% had POCIs and 7% had TACIs. CIMT > 0.9 mm was found in 68.5% of PACI, 66.6% of TACI, 14.2% of POCI and 60% of LACI (p= 0.09). There was no correlation between CIMT and size of infarct (r= 0.132, p= 0.406). CONCLUSION There was significant association between CIMT and acute ischaemic stroke. No association was found between CIMT and brain infarction subtypes. No correlation was found between CIMT and size of infarct.
Authors and Affiliations
Suresh Muthezhathu Kesavadas, Amy Susan George, Roy N
Keywords
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- EP ID EP399058
- DOI 10.14260/jemds/2018/208
- Views 75
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