Cases of GERD in Patients suffering from Idiopathic Pulmonary Fibrosis- A Clinical Study
Journal Title: Harsukh Educational Charitable Society International Journal of Community Health and Medical Research - Year 2018, Vol 4, Issue 2
Abstract
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial disease characterized by the histological pattern of usual interstitial pneumonia. There is evidence of high prevalence of up to 90% of classic gastroesophageal reflux disease (GERD) in IPF in a number of studies. The present study was conducted to study the cases of GERD in patients suffering from IPF. Materials & Methods: The present study was conducted in the department of chest & TB. It consists of 24 cases of IPF. Patients were submitted to pulmonary function tests, and the values of FVC, FEV1, the FEV1/FVC ratio, TLC and corrected DLCO were analyzed. Patients completed a general questionnaire on respiratory and digestive symptoms, as well as the Quality of Life Scale for Gastroesophageal Reflux Disease (GERD-QoL). pH metry was performed in all patients. Results: Out of 24 patients, males were 14 and females were 10. The difference was non- significant (P- 0.1). Out of 24 patients, 10 (41.7%) had GERD. Common symptoms in GERD + patients were heartburn (7), regurgitation (2), epigastic pain (6), dysphagia (3), cough (5) and chest pain (8) and in GERD- patients, heartburn (3), regurgitation (2), epigastic pain (1), dysphagia (2), cough (1) and chest pain (1). The difference was significant (P< 0.05).Conclusion: The prevalence of GERD was higher in patients with IPF. Reflux was more impaired due to esophageal hypomotility, which was more common is these patients.
Authors and Affiliations
Devesh Prasad Mishra
Keywords
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