Catastrophic antiphospholipid syndrome presenting as coronary, cerebral and renal vascular thrombosis: A case report and review of literature
Journal Title: JOURNAL OF MEDICAL COLLEGE CHANDIGARH - Year 2019, Vol 9, Issue 1
Abstract
Catastrophic antiphospholipid syndrome (CAPS) is a rare life-threatening disorder characterized by diffuse vascular thrombosis. It can manifest as microangiopathy, involving small vessels and is associated with presence of lupus anticoagulant and anticardiolipin antibodies. Therapeutic options usually used in CAPS include anticoagulation, steroids, plasma exchange, cyclophosphamide, and intravenous immunoglobulin therapy (IVIG). Although a rare entity, its mortality rate is as high as 50%, so physicians need to be aware of the disease for early detection and treatment of this condition. We hereby report a case of a 36 year old female who was admitted with signs, symptoms and lab investigations suggestive of CAPS and who could not survive even after treatment with IVIG.
Authors and Affiliations
Mandip Singh Bhatia, Ritu Attri, Ishwardip Singh Kwatra, Tarvinderpal Singh
Keywords
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