Causative Organisms and Outcome in Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 10
Abstract
BACKGROUND: Chronic obstructive pulmonary disease and its exacerbations are a major disease problem in Malabar area of Kerala associated with significant morbidity and mortality. AIMS AND OBJECTIVES: 1) To identify the causative organisms responsible for the infective exacerbations of chronic obstructive pulmonary disease. 2) To assess the clinical response to antimicrobial therapy based on sputum culture and sensitivity report. 3)To assess the influence of comorbid conditions in the outcome of chronic obstructive pulmonary disease MATERIALS AND METHODS: A hospital based, non interventional, prospective, study was conducted in the department of respiratory medicine, Pariyaram Medical College, Pariyaram, Kannur, Kerala, India. Study population was 100 consecutive adult COPD patients of either sex. Early morning sputum samples were collected in a sterile container and sent to microbiology department for Gram staining, Culture and sensitivity and acid fast bacilli staining. RESULTS: Among the total 100 patients studied most common age group was 60-69 years (42%).The mean age of study population was 65.6yrs.In this study, males constituted 97% and the rest of them were females. Sputum culture and sensitivity yielded bacterial growth in 67% of study sample.8% patients with fungal growth.25% yielded no growth. Out of 67% of study sample, 29 were streptococcus pneumoniae, which was the most common organism.15 were Hemophilus influenza, 6 were Moraxella catarrhalis and 6 were Klebsiella pneumonia. CONCLUSION: In this study, most of the acute exacerbations of COPD were caused by bacterial infections. The most common organisms isolated were streptococcus pneumoniae
Authors and Affiliations
Dr Smitha Nair P. G
Keywords
Related Articles
- EP ID EP214691
- DOI -
- Views 63
- Downloads 0
Clinical Out Come with Single Dose Ondansetron versus Domperidone in Paediatric Gastroenteritis – Our Experience
Background: Acute gastroenteritis (AGE) is a diarrheal disease of rapid onset, with or without accompanying symptoms and signs, such as nausea, vomiting, fever, or abdominal pain. The WHO recommends ORS as the treatment...
Effect of Drotavarine Hydrochloride and A Combination of - Hyoscine–NButyl Bromide With Valethamate Bromide on the Duration of Active Phase of Labor - A Comparative Study
Labor, an important event, is marked by the fear of pain. Painless and short labor is desired. Obstetricians goal is, healthy neonate and mother. Methods used to shorten active phase of labor are welcomed. Prolonged labo...
Platelet Count to Spleen Diameter Ratio to Predict Esophageal Varices in Patients with Hepatic Cirrhosis
Introduction: The prevalence of esophageal varices in patients with liver cirrhosis may range from60% to 80%, and the reported mortality from variceal bleeding ranges from 17% to 57%In cirrhosis patients the risk of vari...
Effectiveness of Lactational Counseling on Breast Engorgement and Newborn Feeding Behavior among Primigravidae at Sri Ramachandra Hospital
This research study was to assess the effectiveness of the lactation counselling on breast engorgement and newborn feeding behaviour among primigraavidae at Sri Ramachandra Hospital. The research design chosen for the st...
Risk Factors and Prevalence of Hearing Impairment among Neonates in a South Indian Tertiary Neonatal Centre
Background: The prevalence of hearing impairment among NICU graduates is 2-4%.Unidentified hearing impairment at birth can adversely affect speech and language development and can cause long term behavioural difficulties...