CD4+T- Lymphocytes And Alanine Aminotransferases of HIV Positive Patients Co-Infected With Hepatitis B Virus As Seen At The University Of Abuja Teaching Hospital: A 10 Year Retrospective Study.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 3
Abstract
Introduction: Hepatitis B virus infection and HIV infection are both endemic in Sub-Saharan Africa and both have similar routes of transmission. Our aim was to determine the prevalence of HIV/HBV co-infection at the University of Abuja Teaching Hospital, Gwagwalada, and also to study the profile of CD4+ lymphocytes and alanine aminotransferase of patients with HIV/HBV co-infection compared to that of patients with HIV infection alone. Method: The medical records of 1043 HIV patients enrolled into care at the University of Abuja Teaching Hospital from January 2005 to January 2015 were reviewed. Results: Of the 1043 HIV patients that were studied, 116 had a positive HBsAg test, giving an HIV/HBV coinfection prevalence of 11.1%. The gender-specific prevalence rates of co-infection for males and females were 15% and 9.1% respectively (p=0.004).Thoughthe mean serum ALT level among those co-infected was higher (39.0 International Units (IU)/L) compared to those with HIV infection alone (34.5IU/L), this difference was not statistically significant (p=0.05). The mean CD4+ cell count was significantly lower among those withHIV/HBV co-infection (341.96cells/ml) compared to those with HIV infection alone (410.68cells/ml)[p=0.007]. Conclusion: HIV/HBV co-infection is common in our setting; we found a prevalence rate of co-infection of 11.1%. More men than women were co-infected. CD4+ cell count was lower among those with co-infection compared to those with HIV infection alone.
Authors and Affiliations
Vivian Kwaghe, Abdulkareem Lukman
Keywords
Related Articles
- EP ID EP552593
- DOI 10.9790/0853-1803014346.
- Views 71
- Downloads 0
A Study Role of OCT in the evaluation of clinically significant macular edema in diabetic retinopathy
.
Effect of Electromagnetic Radiation on weight of Body And Testis of Albino Rats
Introduction: In modern age everyone are using Mobile Phones even immature children. Nowadays children are spending more time on phone. It has nowadays become an essential part of our lives. Therefore, technological adva...
Effect of Cerebroprote in Hydrolysate Inmanagement of Mild And Moderate Traumatic Brain Injury-An Institutional Study
Introduction: Traumatic brain injury occurs when external force injures the brain which may include falls, violence and vehicle collisions leading to more diffuse injury causing cognitive and neuro psychiatric disturbanc...
Post Dated Pregnancy and Its Outcome
Background: The late- termpregnancy is used to define a pregnancy between 41 weeks and 41 weeks + 6 days, While pregnancy’s at 42 weeks (294 days) and beyond are defined as post term, post dated or prolonged.Incidents of...
Clinical Innovation--Intruding Molar with Spring Loaded Removable Appliance
.