Cellular and Molecular Cascades during Liver Regeneration
Journal Title: Surgical Research – Open Journal - Year 2016, Vol 2, Issue 2
Abstract
The demand for organs such as the liver for patients with end stage disease is greater than what is currently available. Thus, there is a dire need to have alternative solutions, for which none exist at the moment. Investigating the key underlying mechanisms involved not only in liver regeneration and repair, but also in development, can give us a better understanding of how to promote a pro-regenerative phenotype in the liver. This review will focus on the cellular and molecular aspects of liver regeneration and address signaling mechanisms involved in liver development and how they are recapitulated in regeneration after a partial hepatectomy.
Authors and Affiliations
Saeid Amini Nik
Lysine Pill-Induced Esophageal Perforation
Pill-induced esophagitis is being increasingly recognized, but remains largely underreported. Most patients suffer from self-limited pain but complications like esophageal hemorrhage, stricture, perforation and even deat...
Acute Digital Ischemia In a 30-Year Old Man: A Case Report
Objective: To report a rare case of acute digital ischemia at a young man. Methods: A 30-year old man presented with painful bluish discoloration of the toes and palpable pedal pulses. Results: Physical evaluation and ur...
Traumatic Brain Injury: An Update
Traumatic brain injury (TBI) remains one of the leading causes of trauma-related mortality and morbidity in the United States.1 An estimated 2.5 million TBI occur annually resulting in 282,000 hospitalization and 50,000...
The Trans-Diaphragmatic Hydatid Cyst: An Unconventional Surgical Strategy
Introduction: The hydatid disease is a zoonotic infection due to the tapeworm echinococcus granulosus (TEG). In 50-70% of the cases, the hydatid cyst is observed with a hepatic localization. The trans-diaphragmatic exten...
Epidemiologic Analysis of the Surgical Specimens of Breast Carcinosarcomas Examined at a Reference Laboratory in a Nigerian Community
The idea that carcinoma and sarcoma can exist together dated to as early as 1804. Pictorial illustrations of this phenomenon appeared by 1882. Nowadays, with regard to the breast, it is reportedly rare, there being but t...