Cerebral cavernous malformations: epidemiological, clinical and diagnostic imaging aspects
Journal Title: Progress in Health Sciences - Year 2018, Vol 8, Issue 2
Abstract
<b>Introduction:</b> Cerebral cavernous malformations (CCMs) are one of the most common vascular malformations of the central nervous system. Symptoms of CCMs are not typical; the disease can be asymptomatic or be manifested by a wide range of neurological symptoms.<br/><br/><b>Purpose:</b> To evaluate chosen epidemiologic and clinical issues as well as advanced imaging diagnostics of CCMs in computed tomography and magnetic resonance imaging.<br/><br/><b>Materials and methods:</b> The study was based on retrospective analysis of CT and MRI examinations from the 5 years period. The analysis covered 61 persons, 29 males, and 32 females. The CCMs were diagnosed based on MRI examination in 43 patients and CT in 13 patients.<br/><br/><b>Results:</b> The rate of CCMs occurrence in own material was 0.2%. Single lesions were present in 90.2%, while multiple in 9.8% of cases. Supratentorial CCMs were observed in 77% of cases whereas subtentorial in 23%. Mean size of CCMs in the supra- and subtentorial area equaled 10.6±6.3 and 15.1±5.8 mm, respectively (p<0.05). Clinical symptoms occurred in 65.8% of patients, most frequently in patients with CCMs above 5 mm or with subtentorial lesions. All CCMs were hyperdense in CT images, with calcifications in 13.1%. In MRI, malformations showed diverse intensity of the central part with peripheral low-intensity rim of hemosiderine deposits in T2-weighted images.<br/><br/><b>Conclusions:</b> The clinical symptoms occur in most cases of CCMs. These patients require periodic follow-up MRI examinations, specifically those with haemorrhagic incidents or epileptic seizures, with large size or subtentorial CCMs.<br/><br/>
Authors and Affiliations
I. Czekalska, Z. Tyrakowska-Dadełło, P. Werel, E. Tarasów
Keywords
Related Articles
- EP ID EP430355
- DOI 10.5604/01.3001.0012.8316
- Views 86
- Downloads 0
Self-assessment of health condition among patients in long-term nursing home care
Purpose: To determine the health condition self-assessment and the possibility to improve physical functioning of patients in long-term nursing-home care. Materials and Methods: InterRAI-HC (Residential Assessmen...
Prevention and nutritional therapy of metabolic syndrome
The term metabolic syndrome (MetS) defines the cooccurrence of the related risk factors of metabolic origin that promote the development of cardiovascular diseases with atherosclerotic background and type 2 diabetes. The...
Haematological changes among construction workers exposed to cement dust in West Bengal, India
Purpose: This study measured haematological parameters in construction workers exposed to cement dust, silica and other hazardous materials. This was done in order to identify a simple, readily available, and cost effect...
Walking through the lanes of disgust, pain and suffering in the black corridors of sexual exploitation
The authors of this article have seen varied circumstances, situations and scenarios related to the sexual exploitation of young females (generally in the presence of their restricted, prohibited or adverse conditions),...
Assessment of the intensity of procedural pain in newborns treated in the intensive care unit measured by the Neonatal Infant Pain Scale (NIPS)
<b>Introduction:</b> Newborns born prematurely and treated in intensive care units are at greater risk of experiencing pain than patients treated in other units.<br/><br/><b>Purpose:</b> To evaluate the severity of pain...