Cerebral cavernous malformations: epidemiological, clinical and diagnostic imaging aspects

Journal Title: Progress in Health Sciences - Year 2018, Vol 8, Issue 2

Abstract

<b>Introduction:</b> Cerebral cavernous malformations (CCMs) are one of the most common vascular malformations of the central nervous system. Symptoms of CCMs are not typical; the disease can be asymptomatic or be manifested by a wide range of neurological symptoms.<br/><br/><b>Purpose:</b> To evaluate chosen epidemiologic and clinical issues as well as advanced imaging diagnostics of CCMs in computed tomography and magnetic resonance imaging.<br/><br/><b>Materials and methods:</b> The study was based on retrospective analysis of CT and MRI examinations from the 5 years period. The analysis covered 61 persons, 29 males, and 32 females. The CCMs were diagnosed based on MRI examination in 43 patients and CT in 13 patients.<br/><br/><b>Results:</b> The rate of CCMs occurrence in own material was 0.2%. Single lesions were present in 90.2%, while multiple in 9.8% of cases. Supratentorial CCMs were observed in 77% of cases whereas subtentorial in 23%. Mean size of CCMs in the supra- and subtentorial area equaled 10.6±6.3 and 15.1±5.8 mm, respectively (p<0.05). Clinical symptoms occurred in 65.8% of patients, most frequently in patients with CCMs above 5 mm or with subtentorial lesions. All CCMs were hyperdense in CT images, with calcifications in 13.1%. In MRI, malformations showed diverse intensity of the central part with peripheral low-intensity rim of hemosiderine deposits in T2-weighted images.<br/><br/><b>Conclusions:</b> The clinical symptoms occur in most cases of CCMs. These patients require periodic follow-up MRI examinations, specifically those with haemorrhagic incidents or epileptic seizures, with large size or subtentorial CCMs.<br/><br/>

Authors and Affiliations

I. Czekalska, Z. Tyrakowska-Dadełło, P. Werel, E. Tarasów

Keywords

Related Articles

The affective sphere of spouses with high or low relationship satisfaction

Introduction: As a major interpersonal relationship in human life, marriage greatly influences the psycho-physical condition of both husband and wife. Given increasing divorce rates, however, it is crucial for prophylaxi...

Organizational culture in nursing teams based on the example of a particular hospital

Introduction: Organizational culture is a social issue reflecting opinions, behavior or attitudes of members of a particular organization. It determines a sense of identity of the people employed and designates durabilit...

The assessment of empathic understanding and control of emotions in parents of children with autism

Introduction: Problems of families with autism are generally not visible or manifested, but without support, they become economically and educationally inefficient. Purpose: To assess the degree of empathic understanding...

249 Conference Release from the Polish National Conference under the Honorary Patronage of the Minister of Health on “Occupational Safety for Nurses and Midwives”, September 10-11, 2018, Warsaw, Poland

The National Council of Nurses and Midwives organized the Polish National Conference under the Honorary Patronage of the Minister ofHealth on “Occupational Safety for Nurses and Midwives,” held in Warsaw on September 10...

Cell therapy: a new hope for treatment of cerebral palsy ?

Cerebral palsy (CP) is the most frequent neurological disorder associated with perinatal injury of the developing brain. The beneficial impact of stem cells (neural stem cells, mesenchymal stem cells, and embryonic stem...

Download PDF file
  • EP ID EP430355
  • DOI 10.5604/01.3001.0012.8316
  • Views 90
  • Downloads 0

How To Cite

I. Czekalska, Z. Tyrakowska-Dadełło, P. Werel, E. Tarasów (2018). Cerebral cavernous malformations: epidemiological, clinical and diagnostic imaging aspects. Progress in Health Sciences, 8(2), 8-17. https://europub.co.uk./articles/-A-430355