Chalcone: A Versatile Molecule
Journal Title: Journal of Pharmaceutical Sciences and Research - Year 2009, Vol 1, Issue 3
Abstract
Chalcones are 1,3-diphenyl-2-propene-1-one, in which two aromatic rings are linked by a three carbon α,β-unsaturated carbonyl system.These are abundant in edible plants and are considered to be precursors of flavonoids and isoflavonoids. The aim of this review to give summary of methods for synthesis of chalcones, its chemical modifications to flavonoids, flavanone, pyrazoles, oxazoles, pyrimidines. This article also highlights antioxidant potential of chalcone, mechanism of antioxidant activity of chalcones and structure activity relationship of chalcone derivatives for antioxidant ability and different methods to evaluate antioxidant activity of chalcone, antiinflammatory, cytotoxic and antihyperglycemic activity of chalcones is also discussed in this review article.
Authors and Affiliations
Chetana B. Patil , Mahajan S. K. , Suvarna A. Katti
Keywords
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