Change in foveal position based on age and axial length in high myopic eyes
Journal Title: International Journal of Ophthalmology - Year 2018, Vol 11, Issue 5
Abstract
"AIM: To evaluate the influence of age and axial length (AL) on the position of the fovea in patients with high myopia (HM). METHODS: In this prospective study, 96 patients (186 eyes) with HM were consecutively recruited from the Third Affiliated Hospital of Nanchang University. DRI-OCT Atlantis, fundus imaging, and IOL Master were used in this study. Three indices were measured: the distance between the fovea and the optic nerve head (ONH) center (DFO), the vertical distance between the fovea and the horizontal line pass of the ONH center (VDFO), and the horizontal distance between the fovea and the vertical line pass of the ONH center (HDFO). These measurements were used to analyze the effects of different age groups (A1, A2, A3 groups) and AL (AL1, AL2, AL3, AL4 groups) on these indices. RESULTS: The results showed that there was no statistical significance in DFO among the age and AL groups (F=0.46, 0.37; P=0.62, 0.76, respectively). In HDFO, there was also no statistical significance among the age and AL groups (F=0.10, 0.48; P=0.90, 0.69, respectively). In VDFO, however, the difference in the age and AL groups was statistically significant (F=3.21, 3.12; P=0.04, 0.02, respectively). Thus, VDFO were correlated with age and AL (r=0.21, 0.23, all P<0.01), while HDFO and DFO were not correlated with age and AL (r=0.30, P>0.05). CONCLUSION: In high myopia, the foveal position changes mainly in the vertical direction along with factors of age and AL."
Authors and Affiliations
Wei-Feng Liu, Guo-Fu Huang
Critical pathway for primary open angle glaucoma diagnosis
"AIM: To develop a critical pathway for primary open angle glaucoma (POAG) diagnosis intended to be efficient, to unify criteria, reduce resource use and minimize costs to the health system. METHODS: We performed a syste...
Adaptive optics scanning laser ophthalmoscopy in fundus imaging, a review and update
Adaptive optics scanning laser ophthalmoscopy (AO-SLO) has been a promising technique in funds imaging with growing popularity. This review firstly gives a brief history of adaptive optics (AO) and AO-SLO. Then it compar...
Novel mutation in OCRL leading to a severe form of Lowe syndrome
"AIM: To investigate the phenotype and genotype of a family with X-linked recessive Lowe syndrome. METHODS: All the members in the Chinese pedigree underwent comprehensive ophthalmologic and systemic examinations. Genomi...
Correlations between the optic nerve head morphology and ocular biometrics in highly myopic eyes
"AIM: To analyze peripapillary atrophy β/γ zone (PPA-β/γ) and the optic disc ovality index, and to assess their associations with the axial length (AL), refractive error, best corrected visual acuity (BCVA), choroidal th...
Aberrant expression of genes and proteins in pterygium and their implications in the pathogenesis
Pterygium is a common ocular surface disease induced by a variety of factors. The exact pathogenesis of pterygium remains unclear. Numbers of genes and proteins are discovered in pterygium and they function differently i...