Changes in Central Corneal Thickness with Varying Post-prandial Blood Sugar Levels in Type 2 Diabetics
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 3
Abstract
ABSTRACT Introduction: Central Corneal Thickness (CCT) affects measurement of Intraocular Pressure (IOP) using Goldmann Applanation Tonometry (GAT). Variation in CCT with blood sugar levels in diabetics could affect IOP measurement and subsequent glaucoma management. CCT has been described to vary with glycaemic levels in diabetics but variation in CCT in the same individuals with variation in the blood sugar levels has not been adequately described. Aim: To study for changes in CCT in patients with Type 2 Diabetes Mellitus (Ty2DM) during hyperglycaemic blood sugar levels in comparison to euglycaemic blood sugar levels and to look for co-relation if any between changes in blood sugar levels and CCT. Materials and Methods: This was a non-interventional cross- sectional observational study. Ty2DM patients with Post-Prandial Blood Sugar (PPBS) ≥200 mg/dL underwent CCT measurements using optical biometry. CCT was re-measured a month later when they returned for repeat PPBS estimations. Those patients achieving PPBS values <200 mg/dL and a minimum drop of 50 mg/dL were included for analysis. CCT at each visit was measured within 30 minutes of blood sugar measurement. Paired t-test was used to compare mean changes in CCT and PPBS levels. Pearson correlation coefficient was used to assess the relationship between CCT and PPBS levels. Results: The mean CCT of 89 Ty2DM patients with PPBS ≥200 mg/dL was 501.38±25.28 μm. When the PPBS reduced to <200 mg/dL, the CCT was 502.20±25.05 μm. The difference was not statistically significant (p=0.167). There was no correlation between change in blood sugar levels and CCT (Pearson’s r=0.148). Conclusion: The present study demonstrated no significant change in CCT with varying blood sugar levels in Ty2DM patients. Therefore, in routine clinical practice, the correction for GAT IOP based on a single CCT measurement on one occasion, does not have to be revised depending on glycaemic control in Type 2 diabetics.
Authors and Affiliations
Dona George, Arathi Roddam Simha, Andrew Davidbraganza, Lekha Mary Abraham, Yeshvanth Kumar Gubbi Shivanna
Keywords
Related Articles
- EP ID EP581963
- DOI 10.7860/JCDR/2019/40106.12662
- Views 117
- Downloads 0
Effect of Age and Hypertension on Cognition: A Cross-sectional Study
ABSTRACT Introduction: Cognitive impairment has evolved as major health and social issue. As age advances cognitive tasks involving processing speed, working memory and executive function get affected. Cognitive impairme...
Motor Control Training in Chronic Low Back Pain
ABSTRACT Introduction: Chronic Low Back Pain (CLBP) is the most disabling musculoskeletal disorder with altered functioning of the lumbar core muscles. Movement impairment and control impairment syndromes are present in...
Evaluation of Gengigel® Application in the Management of Furcation with Coronally Advanced Flap through Surgical Re-Entry- A Split Mouth Clinical Study
Introduction: One of the challenging and unique periodontal problem of Grade II furcation defect has been managed through different treatment modalities in the past. A successful approach is based on complete closure of...
Comparison of Dexamethasone and Ketorolac as an Adjuvant to Bupivacaine in Axillary Brachial Plexus Blocks for Isolated Hand and Forearm Injuries: A Randomised Double-Blind Prospective Study
ABSTRACT Introduction: Brachial plexus nerve blocks for upper limb surgery provide superior analgesia and reduce opioid consumption. Dexamethasone has been an effective adjuvant to local anaesthetics in brachial plexus b...
Hypertension in Asymptomatic, Young Medical Students with Parental History of Hypertension
Introduction: Family history of hypertension in medical students is an important, non-modifiable risk factor for hypertension in future. Aim: To determine the prevalence of sustained hypertension in young asymptomatic me...