Changes in the spatial distribution characteristics of birth defects and congenital heart disease in Huai'an City, 2016—2022
Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 11
Abstract
Objective To analyze the changes in the spatial distribution characteristics of perinatal birth defects and congenital heart disease (CHD) in Huai'an City, Jiangsu Province, before and after the comprehensive newborn CHD screening program was carried out in 2018, and to provide a scientific basis for adjusting the strategy for prevention and treatment of birth defects in the region. Methods The data were obtained from the perinatal birth defects surveillance data in the Maternal and Child Health Information System of Huai'an City, Jiangsu Province, from 2016 to 2022. The incidence rates of birth defects and CHD in 2016—2018 and 2019—2022 were calculated respectively at the township-level. Global spatial autocorrelation analysis, local spatial autocorrelation analysis and Getis-Ord Gi* hotspot analysis were carried out using ArcGIS Pro 3.2 software. Results The incidence of birth defects and CHD was 8.67‰, 3.67‰ from 2016 to 2022 in Huai'an, respectively. The incidence of birth defects and CHD in 2019—2022 (13.73‰, 7.42‰) were significantly higher than those in 2016—2018 (4.68‰, 0.71‰, P＜0.001). There was no spatial aggregation of birth defects and CHD incidence rates in Huai'an City in 2016—2018; the distribution of birth defects and CHD incidence rates in Huai'an City in 2019—2022 showed a spatial positive correlation distribution, with the hotspot areas all being Licheng Street, Jinnan Township, and Taji Township in the southern part of Jinhu County. In 2019—2022 compared with 2016—2018, all four types of aggregation areas changed. Conclusion Policy adjustments are necessary according to the changes in the incidence and aggregation of birth defects and CHD in different counties. Improving the screening, diagnosis, treatment and monitoring system of CHD, is crucial for the birth defects prevention and control network in Huai'an.
Authors and Affiliations
DING Weijie, WANG Hui, LI Xiaoyu, LU Hongmei, DAI Jiyue, YUE Hongni, JIANG Lulu,ZHU Xiaoqin, XU Xiaolin *Department of Health Care, Huai'an Maternal and Child Health Care Hospital Affiliated to Yangzhou University, Huai'an, Jiangsu 223002, China
Keywords
Related Articles
- EP ID EP751750
- DOI 10.13429/j.cnki.cjcr.2024.11.021
- Views 45
- Downloads 0
Correlation between skeletal muscle mass and islet function in patients with type 2 diabetes mellitus
"<b>Objective</b> To investigate the correlation between skeletal muscle mass and islet function, skeletal muscle mass and insulin resistance in patients with type 2 diabetes mellitus (T2DM), and to elaborate on the clin...
Efficacy of bronchoscopic ablation combined with local injection of endostatin in advanced non-small cell lung cancer patients with intratracheal metastasis
Objective To explore the efficacy and safety of bronchoscopic ablation combined with local injection of endostatin in patients with intratracheal metastasis of advanced non-small cell lung cancer(NSCLC). Methods A retr...
Research progress on denervation in cardiovascular diseases
Denervation is closely related to many cardiovascular diseases, such as myocardial infarction, myocardial ischemia-reperfusion injury, hypertension, arrhythmia, heart failure, atherosclerosis and ventricular remodeling....
Effects of daglipzin on renal function and miR-21-5p and miR-423-5p levels in patients with diabetic nephropathy
Objective</b>To analyze the effects of dapagliflozin on blood glucose levels, renal function, and the levels of miR-21-5p and miR-423-5p in patients with diabetic nephropathy. Methods A total of 98 patients with diabeti...
Influencing factors of lymph node metastasis and construction of a nomogram prediction model in elderly patients with early gastric cancer
"<b>Objective</b> To investigate the factors affecting lymph node metastasis in elderly patients with early gastric cancer (EGC), and construct a risk prediction model based on the nomogram. <b>Methods</b> Sixty-two el...