Changing Trends in Clinical Profile and Management of Liver Abscess? : Prospective Study in a Tertiary Care Hospital.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Background: Though Pyogenic liver abscess is a life threatening disease, there has been significant change in the epidemiology management and mortality over the years. Aim of the study was to review the literature and assess the changing trends in patient presentation and management of liver abscess. Methods: Prospective observational study conducted from May 2013 to May 2015 in Goa Medical College, Goa on 100 patients. In all patients detailedhistory, examination and laboratory investigations were recorded. Mean and chi square test analysis was performed. Results: Of 100 cases reviewed, mean age was 52, most common symptoms were fever and pain (94%) in the right hypochondrium (88%). Most common laboratory abnormality was increased WBC count (70%), deranged liver enzymes ALT AST(50%). Majority of abscess invovled right lobe of liver. Klebsiella pnemoniae was the most common organism isolated (p <0.05). Majority were treated with percutaneous aspirations under ultrasound guidance. Mortality although reported as 11-30% in the present study was 6%. Conclusion; Clinical spectrum of patients with liver abscess seems to have changed with more middle aged male presenting with liver abscess, k.pneumoniae has become a predominantetiology in pyogenic liver abscess. Percutaneous needle aspiration in combination with systemic antibiotics is safe and effective treatment and should be considered as first line treatment.
Authors and Affiliations
Dr. Dattaprasad Samant, Dr. Reshama Salelkar, Dr. Pranav Nagarsenkar,, Dr. F. P. Noronha
Keywords
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- EP ID EP361789
- DOI 10.9790/0853-1707174246
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