CHARACTERISATION OF COAGULASE-NEGATIVE STAPHYLOCOCCI (CoNS) ISOLATED FROM PATIENTS WITH URINARY TRACT INFECTIONS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 29
Abstract
BACKGROUND Species of CoNS have important traits and are frequently associated with various kinds of infections that are manifested clinically. The present study was undertaken to determine the bacterial profile of Urinary Tract Infections (UTI) caused by CoNS and to assess their antibiotic susceptibility pattern. MATERIALS AND METHODS The general principles of collection, transport and storage of specimens are applied. 500 fresh midstream urine samples studied which were collected over a 10-month period from the women and men with a complaint of dysuria who visited the Medical, Surgical and Gynaecological Outpatient Departments of MGM Hospital, Warangal were included in the study. All clinical specimens were processed as per the standard laboratory procedures. Antibiotic susceptibility patterns were determined by Kirby Bauer’s disc diffusion method as per CLSI guidelines. RESULTS Out of 500 urine samples tested, 90 (18%) isolates were coagulase-negative staphylococci and the predominant species was S. saprophyticus. Antibiotic susceptibility testing showed Penicillin resistance of 80%, Amoxicillin resistance of 82.35% and Cephalexin resistance of 58.33%, while majority isolates were sensitive to Vancomycin, Gentamicin and Co-trimoxazole. CONCLUSION The results of the present study show that among the species of CoNS, S. saprophyticus is a major pathogen causing urinary tract infections. It should be supported by antimicrobial susceptibility testing, to prevent the spread of resistant isolates and to promote rational prescribing practices of the antibiotics in that region.
Authors and Affiliations
Geetanjali Tupakula, Kondal Rao, Venkat Krishna Varshith
Keywords
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- EP ID EP538463
- DOI 10.14260/jemds/2018/749
- Views 67
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