Characteristics of liposome used for drug delivery system
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2016, Vol 5, Issue 5
Abstract
Liposome as a drug delivery system is emerges as a one of the potential in pharmaceutical industries. The properties of nano-medicines such as release from dosage forms at specific sites as well as drug circulation and absorption into body membranes are dramatically affected by some physical and chemical characteristics of liposome as a drug delivery system. Zeta potential is a scientific term used for electro kinetic potential in colloidal systems which has a major effect on the various properties of liposome. There are various challenges in the field of drug delivery system, including poor solubility and stability. Presently, colloidal nano-carriers are emerges as a potential drug delivery system. Furthermore, they show an unlimited capacity in the field of drug targeting. Particle size and charge are two major factors which could play key roles in this regard. In this paper synthesis of liposome by extrusion method and the effect of zeta potential and particle size are considered.
Authors and Affiliations
Wajed Khan| Shri Shivaji College of Arts, Commerce and Science, Akola, Pethe. A. S. | Shri Shivaji College of Arts, Commerce and Science, Akola
Keywords
Related Articles
- EP ID EP3749
- DOI -
- Views 402
- Downloads 18
To Evaluate the Clinical Efficacy of Combination of Low Dose Bisoprolol Fumarate and Low Dose Hydrochlorothiazide with Bisoprolol Alone in Stage I and II Hypertension
OBJECTIVE: Control of hypertension by the use of low dose combination therapy is associated with greater efficacy, less side effects and higher response rates as the result of complementary mechanisms of antihypertensiv...
Prevalence of MRSA nasal colonization among community members and healthcare workers at private and public hospitals in Khartoum State, Sudan.
Background:MRSA is a growing public health threat around the world. Until now, we are still unable to control the spread of staphylococcal infection and the development of resistance. Objectives: To determine the prevale...
The Role and Significance of C – Reactive Protein in Neonatal Sepsis: A Clinical Investigation
OBJECTIVE: To evaluate the role of CRP in the management of neonatal sepsis in a NICU setting where resources for diagnosis and monitoring prognosis is minimal. METHODOLOGY: The study was conducted at Dr. B.R. Ambedkar...
CLINICO-MICROBIOLOGICAL PROFILE OF COMMUNITY ACQUIRED PNEUMONIA IN A TERTIARY CARE HOSPITAL
Community Acquired Pneumonia (CAP) is a frequently encountered lower respiratory tract parenchymal lung infection which continues to be a major health problem leading to significant morbidity and mortality worldwide. Eti...
Development of Stability-Indicating Liquid Chromatographic Method for Analysis of Cefoxitin Sodium in Sterile Formulation.
Stability-indicating high performance liquid chromatography (HPLC) method was developed and validated for analysis of cefoxitin sodium in its powder for injection dosage form. Chromatographic separation was achieved on...