Characterization and management of β- lactamases producing Escherichia coli causing complicated UTIs in an era of antimicrobial resistance
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 8
Abstract
Urinary tract infections (UTIs) are among the most common infectious diseases in the community as well in healthcare settings.1 A complicated UTI is defined as an infection of urinary tract that is associated either with structural or functional genito-urinary tract abnormalities or in the presence of an underlying factors like foreign bodies (such as calculi, indwelling catheters), obstructions, immune-suppression, renal failure, pregnancy etc., which increases the risk of acquiring an infection or of failing therapy. Complicated UTIs (cUTIs) may occur in both the sexes and in all age groups.2,3 There is a broad range of pathogens that can cause cUTI and Escherichia coli remains the most common. In the past few years, the number of cases of cUTI due to resistant Escherichia coli has risen, mainly due to spread of β-lactamase producing bacteria posing a significant therapeutic challenge.4
Authors and Affiliations
Dr. Nitin Gupta
Keywords
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