Chemotherapy for Retinoblastoma
Journal Title: IP International Journal of Ocular Oncology and Oculoplasty - Year 2016, Vol 2, Issue 4
Abstract
Retinoblastoma is the most common primary malignant intraocular tumor of childhood. It has a mortality close to 60% in the developing world. With early diagnosis and treatment, survival rates could be high as 95%. Management of Retinoblastoma has undergone a paradigm change in the past two decades with globe salvage becoming the goal of treatment. Safety and efficacy of chemotherapeutic agents combined with their targeted delivery has increased the success rates of tumor control. This article reviews the treatment strategies using different routes of drug delivery to contain ocular and extraocular retinoblastoma, the risks and benefits and future of chemotherapy.
Authors and Affiliations
Rajarathna Thangavel, Hakan Demirci
Keywords
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