Chromosomal Abnormalities in Infertile Men with Azoospermia and Oligospermia
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 5
Abstract
The present study was carried out to find out frequency of chromosomal abnormalities in infertile males with azoospermia& oligospermia.50 males referred for complaints of infertility with azoospermia & oligospermia were included in the present study. The study was carried out in the following steps. 1) Selection of patients 2) Clinical examination of patients 3) Collection of blood and karyotyping 4) Photomicrography 5) Data tabulation and Analysis. Among the total 25 azoospermic males, 8 patients showed abnormal karyotype. Among these abnormal karyotypes, 3 patients showed 47XXY karyotype, 2 patients showed 46XX karyotype, 46XY(20%)/47XXY(80%) was found in 1 patient, 1 patient showed 47,X,i (Xq)Y & 1 patient showed a 45,XY,-22 t (14/22) karyotype. Seventeen patients had normal karyotype. Among the total 25 oligospermic male, 3 patients showed abnormal karyotype. Among these abnormal karyotype, 1 patient showed mosaic Klinefelter i.e. 46XY(20%)/47XXY(80%), 1 patient showed a karyotype of 46,XY, inv(9) and one patient showed 46,XY, large Y.
Authors and Affiliations
Drugkar Amol Z.
Keywords
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