Chronic Osteomyelitis: Aetiology and Antibiotic Susceptibility Pattern

Abstract

Background: Chronic osteomyelitis is a persistent disease, difficult to treat or eradicate completely. In the absence of early diagnosis and prompt treatment or due to development of drug resistance, chronic osteomyelitis is still an important cause of high morbidity. Pus culture and sensitivity will yield the causative organism and help in selecting the appropriate antibiotics. Methodology: 100 pus samples taken aseptically were cultured on Blood and MacConkey agar plates aerobically at 37oC for 18-24 hrs. Culture isolates were identified by a series of standard biochemical reactions. Antibiotic susceptibility was performed as per CLSI guidelines. Results: Study group comprised73males and 27 females. Majority of the patients were in the age group of 11 – 50 years (77%) with trauma being the most common (44%) predisposing factor. The commonest organisms isolated were Staphylococcus aureus (35%) and Pseudomonas aeruginosa (17%). Majority of Gram positive organisms were sensitive to Amikacin, Linezolid, Vancomycin and Gram negative organisms to Amikacin and Imipenem. Conclusion: The wide range of causative organisms and degree of resistance to commonly used anti-microbials supports the importance of pus culture and provides important information to guide clinician’s choice of empirical antibiotics.

Authors and Affiliations

Mita D. Wadekar , Venkatesha D , Anuradha K

Keywords

Related Articles

Assessment of Conception Rate in Infertile Couples with Genital Tuberculosis Diagnosed with Multiplex Polymerase Chain Reaction

Objective: Mycobacterium infections of genital tract of couple have an impact on fertility. Both suspected male or female were subjected to investigation of genital TB and treating the affected or the couple and rise in...

Study of Causes of Maternal Mortality Over a Decade

Introduction: Maternal mortality is an important indicator of the reproductive health of the society, overall effectiveness of the obstetric health care system and also of the general health care system of that country....

Functional and Radiological Outcomes of Distal Radius Fractures Treated with Closed Reduction and Percutaneous Five Pin Technique – A Prospective Cohort Study

Distal radius fractures are one of the most common fractures occurring in adults. Despite several advances, the ideal treatment is yet to be agreed upon. Traditional methods of reduction and plaster have been associated...

A Study on Determinants of Unmet Need for Family Planning Among Married Women in Urban Slum Area

Introduction: According to UN projections India’s population will reach 1.53 billion by the year 2050, and will be the highest population in the world. . For limiting the number of children, the concept of unmet need wil...

Unusual Arterial Variation of Upper Limb – Case Report.

Brachial artery, which is continuation of axillary artery extending from lower border of teres major muscle up to the neck of radius, where it divides into radial and ulnar arteries.In the present case two arteries in th...

Download PDF file
  • EP ID EP104974
  • DOI -
  • Views 108
  • Downloads 0

How To Cite

Mita D. Wadekar, Venkatesha D, Anuradha K (2014). Chronic Osteomyelitis: Aetiology and Antibiotic Susceptibility Pattern. INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY, 9(3), 337-340. https://europub.co.uk./articles/-A-104974