Circulating miRNAs as Predictor Markers for Activation of Hepatic Stellate Cells and Progression of HCV-Induced Liver Fibrosis.
Journal Title: Electronic Physician - Year 2016, Vol 8, Issue 1
Abstract
Liver fibrosis is the excessive accumulation of extracellular matrix that occurs by activation of hepatic stellate cells (HSCs), which has been identified as the major driver of liver fibrosis. Several studies confirmed that miRNAs have regulatory effects on the activation of HSCs by affecting the signaling pathways. The aim of this study was to develop non-invasive diagnostic markers by measuring different circulating miRNAs in serum as predictor markers for early diagnosis of liver fibrosis and its progression.
Authors and Affiliations
Eman El-Ahwany, Faten Nagy, Mona Zoheiry, Mohamed Shemis, Hoda Abu Taleb, Maged El Ghannam, Rafaat Atta, Suher Zada
Keywords
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- EP ID EP123141
- DOI 10.19082/1804
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