Clarifying the term "evidence based medicine"
Journal Title: Αρχεία Ελληνικής Ιατρικής - Year 2015, Vol 32, Issue 6
Abstract
Although the term evidence based medicine (EBM) is part of the everyday medical vocabulary, there is often considerable confusion over its meaning. In Greece, an additional reason for misconceptions lies in the translation of the word "evidence" into Greek words meaning either "proof" or "documentation". Instead of personal experience and pathophysiological rationale, on which medical decisions were based in the past, EBM uses evidence from clinical research, which is mainly represented by randomized control trials (RCTs), in making decisions about the care of individual patients. An updated model for evidence based clinical decision making integrates research evidence with clinical expertise and the choice of patients. Criticism of EBM covers a wide variety of topics, including shortage of scientific evidence ("gray zones"), paucity of documentation that EBM improves patient outcome, early discontinuation or non-publication, non-registration and clinical irrelevance of completed RCTs, and various limitations of the guideline process, such as lack of established working rules and conflict of interest in guideline committees. To address the above concerns, many experts call for a return to the founding principles of EBM. Despite its flaws, EBM remains an indispensable aid to clinical decision making.
Authors and Affiliations
T. MOUNTOKALAKIS
Development of hyponatremia
No abstract available
Νομικές ρυθμίσεις για την ψυχοκοινωνική αποκατάσταση των ασθενών στο Βυζάντιο <br /> <br />
Βασική καινοτομία της βυζαντινής περιόδου αποτελεί η διασφάλιση και η αποκατάσταση του ψυχιατρικού αρρώστου. Θεσπίζεται ο προγαμιαίος ιατρικός έλεγχος, για την προστασία των μελλονύμφων από ασθένειες όπως η μανία, η επιλ...
Blood culture in the initial work-up of community-acquired pneumonia
OBJECTIVE Blood culture (BC) is considered part of the initial laboratory examination of hospitalized patients with community-acquired pneumonia (CAP), although recent studies have challenged the necessity of such practi...
Pneumocystis carinii pneumonia (PCP)
No abstract available
The genetic deficiency of aquaporin 7 is implicated in the development of obesity <br /> <br /> The genetic deficiency of aquaporin 7 is implicated in the development of obesity
The understanding of the movement of water through cell membranes has been greatly advanced by the discovery of a family of water specific membrane plasma proteins, the aquaporins. Aquaporins are present at all levels of...