Clinical and Epidemiological Characteristics of Pituitary Tumours using a Web-based Pituitary Tumour Registry in Oman
Journal Title: Sultan Qaboos University Medical Journal - Year 2007, Vol 7, Issue 1
Abstract
Objective: From a recently instituted web-based pituitary tumour registry at Sultan Qaboos University Hospital, Oman, this study explores the results of comprehensive clinical evaluation, hormonal levels, radiological evidence of pituitary mass lesion using magnetic resonance (MRI) and the different treatment modalities. Methods: All patients who were diagnosed with pituitary mass tumours in our tertiary care endocrinology clinic between January 998 and February 2006 were registered in the Oman pituitary tumour registry. Two physicians performed hospital chart review and data entry. Results: A total of 60 entries were made into the pituitary tumour registry. Te overall mean age of the cohort was 32 ±2 years (age range 8-73 years). Te majority of registrations were female (n=4; 7%). Tere were 8 patients with non-functioning adenomas (50.6%), 59 with prolactinoma (36.9%) eight with acromegaly (5%), seven with craniopharyngioma (4.4%), four with Cushing’s disease (2.5%) and one with sarcoidosis (0.6%). Sub-group analyses were done only for the subjects with the 3 most prevalent pituitary tumours (non-functioning adenomas, prolactinomas, and acromegaly). Te most prevalent symptoms are amenorrhea-galactorrhea (n=55; 37%), headache (n=3; 2%) and fatigue (n=23; 6%). Te most common treatment modality was medical (n=58; 39%), followed by observation (n=56; 38%), surgery (n=3; 2%) and surgery plus medical (n=3; 2%). None of the patients in this registry are recorded to have died. Conclusion: To our knowledge, this is the first pituitary tumour registry in the Arabian Gulf countries using a web-based programme. Tis tumour registry will enable us to characterize clinical and the epidemiological features of pituitary tumours in the Sultanate of Oman.
Authors and Affiliations
Abdullah Al-Futaisi| Department of Medicine, Sultan Qaboos University, P. O. Box 35, Al-Khod 123, Sultanate of Oman, Al-Yaarubi Saif| Department of Medicine, Sultan Qaboos University, P. O. Box 35, Al-Khod 123, Sultanate of Oman, Ibrahim Al-Zakwani | Department of Pharmacy, Sultan Qaboos University Hospital, P. O. Box 35, Al-Khod 123, Sultanate of Oman, Salim Al-Qassabi| Department of Medicine, Royal Hospital, Muscat, Oman, Shaden Al-Riyami| Child Health Department, College of Medicine & Health Sciences, Sultan Qaboos University, P. O. Box 35, Al-Khod 123, Sultanate of Oman, Yasser Wali| Child Health Department, College of Medicine & Health Sciences, Sultan Qaboos University, P. O. Box 35, Al-Khod 123, Sultanate of Oman
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