Clinical and Metabolic changes after the Non- surgical Periodontal Therapy in patients with Type-2 Diabetes Mellitus with Chronic periodontitis with or without the Systemic administration of Azithromycin - A Randomized Controlled Clinical Trial
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 3
Abstract
Background & Objectives: There is growing evidence that periodontitis may affect general health. Periodontal disease is now recognized as the sixth complication of diabetes. It has been suggested that an alteration in glucose metabolism occurs as a result of antibacterial periodontal therapy. The present study is aimed to evaluate the clinical and metabolic changes in type-2 diabetic patients with chronic periodontitis after non-surgical periodontal therapy with or without the systemic administration of azithromycin. Method: In our study24 patients with type-2 diabetes having chronic periodontitis were included. Group I included 12 patients who underwent scaling and root planing (SRP) only and group II 12 patients who underwent SRP with concomitant systemic administration of azithromycin 500mg once daily for 3 days. At baseline, plaque index (PI), gingival index (GI), probing depths (PD) were recorded and glycated haemoglobin (HbA1c) levels were evaluated. Patients were followed for 30-90 days. Results: The mean decreasein glycosylated hemoglobin (HbA1c) was 0.18± 0.5 after nonsurgical periodontal treatment in group I on comparing the baseline (8.98± 0.99) and final values (8.8± 1.10), and in group II was 1.18± 0.47on comparing the baseline (9.01± 1.18) and final values (3.36± 1.87) proved statistically significant (P≤ 0.05). Conclusion: A decrease in HbA1c was observed in group II (SRP+Azithromycin 500mg once daily3 days) thus indicating improved blood glucose control in Type 2 diabetics with periodontal disease compared to group I (SRP only).
Authors and Affiliations
Dr Madanika P
Keywords
Related Articles
- EP ID EP511336
- DOI -
- Views 59
- Downloads 0
Post-graduate Resident, Department of Community Medicine, Government Medical College, Nagpur 440003 India
Background: Laptop which is always in contact with the hand during working may act as a medium of transmission of the disease. The Objective: The researchers conducted a bacteriological test on laptops to know the quanti...
Efficacy of Proprioceptive Neuromuscular Facilitation techniques to Pelvic girdle muscles in improving gait in hemiplegic patients
Objectives: To compare the effects of PNF treatment applied to the pelvic region in patients with hemiplegia acute and chronic stage and investigate whether the duration of hemiplegia affected the results of the treatmen...
A Review on Recent Advances in Drug Development and Pharmacotherapeutic Approaches for Obesity
Overweight and obesity are defined as abnormal or excessive fat accumulation that presents a risk to health. A crude population measure of obesity is the body mass index (BMI) . A person with a BMI of 30 or more is gener...
Seven Accessory (Supernumerary) Thoracic Ribs in Left Thoracic Wall: A Case Report
Common rib anomalies include cervical ribs, bifid ribs, rib dysplasia, and intercostal fusion. The term “intrathoracic rib” signifies abnormal location of a rib within the thoracic cavity. An intrathoracic rib is a rare...
Review of Shunthi (Zingiber officinale Rosc.) in Ayurvedic Literature
Shunthi (Zingiber officinale Rosc.) belongs to Zingiberaceae family. It is a perennial erect herb with a creeping tuberous rhizome. Root stock horizontal, tuberous, aromatic, stout, rhizome with erect leafy stems 0.6-1.4...