Clinical and pathological features of isolated pulmonary and liver recurrences in endometrial cancer.
Journal Title: Medical Science and Discovery - Year 2016, Vol 3, Issue 1
Abstract
Objective: To present the clinicopathological features of endometrial cancer (EC) patients with isolated liver or lung metastases and to compare the survival differences after diagnosis of recurrent disease. Material and Methods: The clinical and histopathological data of the patients who were treated with a diagnosis of epithelial EC between January 1993 and May 1993 at Etlik Zubeyde Hanim Teaching and Research Hospital were retrospectively reviewed. Patients with isolated recurrence in liver (ILR) or lung (IPR) were included in the analysis.Results: The clinical data of 162 patients with recurrent EC were available. Of these, 21 had IPR and 9 had ILR. Patients with ILR presented with more advanced stage, and omental and adnexal involvement was more common compared to patients with IPR. On the other hand, patients with IPR had higher grade disease. Fifty-seven percent of patients with IPR had grade 3 compared to 11% of grade 3 disease in ILR (p=0.02). The median time to recurrence (TTR) was 18 months (range 1-54) in the whole study population. While the median TTR of patients with IPR was 19 months, the median TTR of patients with ILR was 16 months (p=0.204). Both study groups have similar survival. The 1-year post-recurrence survival of IPR and ILR was 66% and 56% (p=0.129), respectively.Conclusion: Although, isolated liver and lung metastases are the result of hematogenous spread in EC, clinicopathological features of these two recurrence patterns significantly differ. Clinicians should try to categorize these patients separately to better understand the prognostic outcomes.
Authors and Affiliations
Derman Basaran, Isin Ureyen, Mustafa Karalok, Osman Turkmen, Gunsu Kimyon, Mehmet Celik, Tolga Tasci, Ahmet Turan
Keywords
Related Articles
- EP ID EP520470
- DOI -
- Views 57
- Downloads 0
Documentation of the Salivary Gland Tumors: An Institutional Data From Turkey
Objective: World-wide series show some differences in the incidence and clinicopathologic features of salivary gland tumors.Methods: A total of 248 cases of SGTs diagnosed in our hospital between 1998 and2013 were review...
An important paraplegia case due to synthetic cannabinoid bonsai abuse
The number of synthetic derivatives of the world’s most popular and commonly abused drug, cannabis is rapidly growing dayby day. Although the drug has certain applications in the medical field, due to its wide and easy a...
Shoulder ganglion cysts in MRI: accompanying tendon pathologies and labral lesions
Objective: The aim of this study was to investigate shoulder tendon pathologies and labral lesions that accompanied with ganglion cysts on the shoulder via magnetic resonance imaging (MRI). Material and Metho...
The relationship between illness perception and quality of life in thyroid patients who received radioactive iodine-131 ablation treatment
Objective: Most of the differentiated thyroid carcinoma (DTC) patients recover totally after the primary treatment. Unlike most of the other cancer types, the patients do not go through a long, challenging and weary trea...
PERIOPERATIVE CONTROL OF BLOOD GLUCOSE
This review mainly focuses on the management of type 2 diabetes in the preoperative setting with a special emphasis on intraoperative glycemic control. Some patients learn their diagnosis of diabetes just prior to the su...