Clinical Effects of Intrathecal Ropivacaine and Ropivacaine with Dexmedetomidine in Inguinal Hernia Cases
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 3
Abstract
Abstract Introduction: Ropivacaine is a first single enantiomer-specific compound, which has a reduced risk of cardiotoxicity, neurotoxicity, and rapid recovery of motor function. Post-operative pain relief is an important issue with ropivacaine. It has been used with many adjuvants for lower limb surgery, which has other side effects. Aim: Aim of the study was to compare the clinical effects of intrathecal ropivacaine and ropivacaine with dexmedetomidine. Materials and Methods: Inguinal hernioplasty cases were included in the study. Group 1 administered with 0.75% isobaric ropivacaine 3 ml + 0.5 ml normal saline and Group 2 administered with 0.75% isobaric ropivacaine 3 ml + 5 mg dexmedetomidine in 0.5 ml normal saline. Results: Onset of sensory and motor block was early in Group 2 patients than Group 1 (Group 2 5.58 ± 3.56 > 8.0 ± 1.8 in Group 1) with the P <0.05. Postoperatively Group 2 patients had delayed two segment regression and S2 segment regression, than Group 1 patients. (P < 0.0001). In Group 2, patients out of 29 patients two patients were developed bradycardia with hypotension. Motor block duration was more with Group 2 patients than Group 1 (P > 0.05). Time of getting rescue analgesia is very much delayed in Group 2 than Group 1 (P < 0.0001). Conclusion: Ropivacaine is a newer ideal, comfortable safe anesthetic of choice for intrathecal use in inguinal hernia surgery cases, American Society of Anesthesiologists (ASA I and II) and by adding dexmedetomidine we get a prolongation of analgesia.
Authors and Affiliations
R Srinivasan, Heber Anandan
Keywords
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