Clinical Efficacy of Actovegin in Complex Treatment of Patients with Diabetes Mellitus Type 2 with Diabetic Polyneuropathy Against Arterial Hypertension
Journal Title: Міжнародний ендокринологічний журнал - Year 2013, Vol 2, Issue 50
Abstract
The aim of the study — to evaluate the clinical efficacy of Actovegin in complex treatment of patients with diabetes mellitus (DM) type 2 diabetic polyneuropathy (DPN) with arterial hypertension (AH). We observed 53 patients with DM type 2 with DPN against AH, who served as controls (n = 25) and study (n = 28) group. Patients of study group in addition to the basic therapy received intravenous infusions of 400 mg of Actovegin for 10 days. It is found that the use of Actovegin in comprehensive treatment of DM type 2 with DPN against AH improves the clinical picture of the disease, which is associated with reduction in intensity of thirst, dry mouth, weakness, rapid fatigability, headache and dizziness, normalization of blood pressure. Actovegin has a positive effect on symptoms of DPN, resulting an increase in all kinds of sensitivity, decrease in degree of pain syndrome. Administration of Actovegin in the treatment of DM type 2 improves the glycemic profile, reduces the level of peripheral insulin resistance, and also has a beneficial potentiating action on the abnormal lipid metabolism.
Authors and Affiliations
I. V. Pankiv
Keywords
Related Articles
- EP ID EP232761
- DOI -
- Views 51
- Downloads 0
Features of Treatment of Patients with Diabetes Mellitus Type 2 with Heart Failure (Literature Review)
Diabetes mellitus and heart failure are often comorbid conditions. The studies found that patients taking metformin as monotherapy (odds ratio 0.65 (0.48–0.87)) or in conjunction with other drugs (0.72 (0.59–0.90)), mort...
Carbohydrate Metabolism in Young Women with Primary Obesity
We have studied the carbohydrate metabolism in 241 young women — 16–45 years (mean age — 28.5 ± 7.0 years) with primary obesity (body mass index 26 to 62 kg/m2). It was found that 64 % of women with primary obesity had...
Prevalence of autoimmune thyroiditis among women with vitamin D deficiency
Background. Vitamin D and its metabolites play an important clinical role due to their interrelationship with calcium homeostasis and bone metabolism. Vitamin D has major effects on nearly all cells of the immune system....
Associations between Mycoplasma and Components of Immune Response in Women with Autoimmune Thyroiditis
There was investigated immunoglobulin G (IgG) to the mycoplasma (Mp) in the blood serum of women with autoimmune thyroiditis (AIT) of reproductive age and in postmenopausal periods. A control group consisted of women of...
Evaluating the prevalence and analysis of the main risk factors of type 2 diabetes mellitus among residents of Aktobe and Aktobe region (Republic of Kazakhstan)
Background. In the emergence and progression of chronic non-infectious diseases, risk factors play an important role, which are common to many diseases, and with simultaneous action they potentiate the influence of each...